Business Hotels in Chillicothe, OH
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Featured Chillicothe Business Hotels

Quality Inn & Suites
24517 US Highway 23 S Circleville OH
$77 nightly
The price is $87 total per night
$87 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn & Suites Circleville features a 24-hour gym, free WiFi in public areas, and meeting rooms. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Breakfast included

Fairfield Inn and Suites by Marriott Chillicothe
300 North Plaza Boulevard Chillicothe OH
Free Cancellation
Reserve now, pay when you stay
$170 nightly
The price is $195 total per night
$195 total
Dec 30 - Dec 31
Total with taxes and fees
At Fairfield Inn and Suites by Marriott Chillicothe, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, securing valuables, and tours or tickets. Additional amenities include a 24-hour business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Christopher Inn and Suites
30 North Plaza Boulevard Chillicothe OH
Free Cancellation
Reserve now, pay when you stay
$120 nightly
The price is $138 total per night
$138 total
Dec 18 - Dec 19
Total with taxes and fees
Christopher Inn and Suites features free WiFi in public areas, a conference center, and free newspapers. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include laundry facilities, a vending machine, and a picnic area.
Breakfast included
Parking included

Comfort Inn
7525 US 23 Piketon OH
$95 nightly
The price is $108 total per night
$108 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
Guests of Comfort Inn Piketon near Fairgrounds enjoy a gym, free WiFi in public areas, and conference space. Free parking is available if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included

Quality Inn
605 E Main St Jackson OH
At Quality Inn Jackson, guests have access to a gym, free WiFi in public areas, and a business center. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a meeting room, free newspapers, and a vending machine.
Breakfast included
Parking included

Quality Inn Chillicothe
20 N Plaza Blvd Chillicothe OH
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $117 total per night
$117 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Quality Inn Chillicothe enjoy a gym, free WiFi in public areas, and meeting rooms. A stay here includes free parking. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a conference center, a business center, and a seasonal outdoor pool.
Pool
Breakfast included

Best Western Adena Inn
1250 N Bridge Street Chillicothe OH
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $118 total per night
$118 total
Dec 18 - Dec 19
Total with taxes and fees
Guests of Best Western Adena Inn enjoy access to free WiFi in public areas, conference space, and a business center. There's free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, a computer station, and free newspapers.
Pool
Breakfast included

Red Roof Inn Jackson, OH
1000 Acy Ave Jackson OH
Free Cancellation
Reserve now, pay when you stay
$97 nightly
The price is $113 total per night
$113 total
Dec 17 - Dec 18
Total with taxes and fees
Guests of Red Roof Inn Jackson, OH enjoy a gym, free WiFi in public areas, and coffee in a common area. The 24-hour front desk has staff standing by to help with tours or tickets, and answer any questions about the accommodations. Additional amenities include a meeting room, express check-out, and a vending machine.
Pet friendly
Free WiFi

Holiday Inn Express Circleville by IHG
23911 Us Rt 23 S Circleville OH
Free Cancellation
$74 nightly
The price is $84 total per night
$84 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Circleville by IHG features a 24-hour gym, free WiFi in public areas, and conference space. You can take advantage of free parking if you drive. The front desk has multilingual staff standing by 24 hours a day to assist with securing valuables and dry cleaning/laundry. Additional amenities include a 24-hour business center, coffee/tea in a common area, and free newspapers.
Breakfast included
Pet friendly

Ameristay Hotel Inn & Suites Waverly
800 W. Emmitt Ave Waverly OH
$100 nightly
The price is $110 total per night
$110 total
Dec 17 - Dec 18
Total with taxes and fees
Guests of Ameristay Hotel Inn & Suites Waverly have access to an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a hot tub, a business center, and a microwave in a common area.
Pool
Hot Tub

Hampton Inn & Suites Chillicothe
100 N Plaza Blvd Chillicothe OH
Free Cancellation
Reserve now, pay when you stay
$149 nightly
The price is $170 total per night
$170 total
Jan 15 - Jan 16, 2026
Total with taxes and fees
Guests staying at Hampton Inn & Suites Chillicothe enjoy an indoor pool, a gym, and free WiFi in public areas. Onsite parking is offered for a fee. Front-desk staff can answer questions 24/7, and assist with tours or tickets, securing valuables, and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Holiday Inn Express Chillicothe East by IHG
1003 E Main Street Chillicothe OH
Free Cancellation
$112 nightly
The price is $128 total per night
$128 total
Jan 16 - Jan 17, 2026
Total with taxes and fees
At Holiday Inn Express Chillicothe East by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Chillicothe hotels essential information
Accommodation | 2,617 hotels |
|---|---|
Lowest Price | $84 |
Highest Price | $195 |
Popular hotels | Quality Inn & Suites, Fairfield Inn and Suites by Marriott Chillicothe, Christopher Inn and Suites, Comfort Inn, Quality Inn, Quality Inn Chillicothe, Best Western Adena Inn, Red Roof Inn Jackson, OH, Holiday Inn Express Circleville by IHG, Ameristay Hotel Inn & Suites Waverly, Hampton Inn & Suites Chillicothe, Holiday Inn Express Chillicothe East by IHG |
Recent Business Hotels Reviews

Sonesta Columbus Downtown
5/5 Excellent
"The hotel staff was very attentive and helpful! The room we stayed in was very clean!"
A verified traveler stayed at Sonesta Columbus Downtown
Posted 2 days ago


