Business Hotels in Buffalo, WY
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Featured Buffalo Business Hotels

Hampton Inn & Suites Buffalo
85 Us Highway 16 E Buffalo WY
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $100 total per night
$100 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Hampton Inn & Suites Buffalo have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include meeting rooms, a conference center, and a 24-hour business center.
Pool
Breakfast included

Holiday Inn Express & Suites Buffalo by IHG
106 East Highway 16 Buffalo WY
Free Cancellation
$89 nightly
The price is $100 total per night
$100 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of Holiday Inn Express & Suites Buffalo by IHG have access to an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, conference space, and a business center.
Pool
Hot Tub

Buffalo Inn
100 Flatiron Drive Buffalo WY
Free Cancellation
Reserve now, pay when you stay
$44 nightly
The price is $49 total per night
$49 total
Jan 24 - Jan 25, 2026
Total with taxes and fees
Buffalo Inn features free WiFi in public areas, a 24-hour business center, and coffee in a common area. There's free parking and an area shuttle for a fee. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a meeting room, a library, and free newspapers.
Pet friendly
Parking included

Quality Inn
75 N Bypass Rd Buffalo WY
Free Cancellation
Reserve now, pay when you stay
$47 nightly
The price is $53 total per night
$53 total
Jan 19 - Jan 20, 2026
Total with taxes and fees
Guests of Quality Inn Buffalo enjoy a 24-hour gym, free WiFi in public areas, and meeting rooms. Free parking is available if you drive. The 24-hour front desk has multilingual staff ready to assist with luggage storage and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include a conference center, a business center, and a seasonal outdoor pool.
Pool
Breakfast included

SureStay Plus Hotel by Best Western Buffalo
65 US Highway 16 East Buffalo WY
Free Cancellation
Reserve now, pay when you stay
$77 nightly
The price is $86 total per night
$86 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At SureStay Plus Hotel by Best Western Buffalo, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include meeting rooms, a 24-hour business center, and free newspapers.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Buffalo hotels essential information
Accommodation | 246 hotels |
|---|---|
Lowest Price | $49 |
Highest Price | $100 |
Popular hotels | Hampton Inn & Suites Buffalo, Holiday Inn Express & Suites Buffalo by IHG, Buffalo Inn, Quality Inn, SureStay Plus Hotel by Best Western Buffalo |
Recent Business Hotels Reviews

Holiday Inn Express & Suites Buffalo by IHG
5/5 Excellent
"Great stay"
A verified traveler stayed at Holiday Inn Express & Suites Buffalo by IHG
Posted 8 days ago


