Business Hotels in South Sioux Falls, SD
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured South Sioux Falls Business Hotels

Towneplace Suites Sioux Falls South
6400 S Connie Avenue Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$107 nightly
The price is $119 total per night
$119 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Towneplace Suites Sioux Falls South, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub

Courtyard by Marriott Sioux Falls
4300 W Empire Pl Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$92 nightly
The price is $103 total per night
$103 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Guests of Courtyard by Marriott Sioux Falls have access to an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

Candlewood Suites Sioux Falls by IHG
2725 S Carolyn Ave Sioux Falls SD
Free Cancellation
$99 nightly
The price is $111 total per night
$111 total
Dec 30 - Dec 31
Total with taxes and fees
Candlewood Suites Sioux Falls by IHG features a 24-hour gym, free WiFi in public areas, and a business center. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a computer station, express check-in, and express check-out.
Pet friendly
Parking included

AmericInn by Wyndham Sioux Falls
3508 S Gateway Blvd Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $75 total per night
$75 total
Dec 28 - Dec 29
Total with taxes and fees
AmericInn by Wyndham Sioux Falls features an indoor pool, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. Additional amenities include a business center, free newspapers, and laundry facilities.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Sioux Falls
4521 W. 41st Street Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $90 total per night
$90 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Sioux Falls have access to an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with a free area shuttle. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a hot tub, conference space, and a business center.
Pool
Hot Tub

Staybridge Suites Sioux Falls by IHG
2505 S Carolyn Ave Sioux Falls SD
Free Cancellation
$97 nightly
The price is $108 total per night
$108 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Staybridge Suites Sioux Falls by IHG, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a hot tub, a business center, and a meeting room.
Pool
Hot Tub

Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2501 S Shirley Ave Sioux Falls SD
Free Cancellation
$126 nightly
The price is $140 total per night
$140 total
Dec 29 - Dec 30
Total with taxes and fees
Guests of Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has multilingual staff ready to assist with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

SpringHill Suites by Marriott Sioux Falls
4304 W Empire Pl Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$92 nightly
The price is $103 total per night
$103 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests staying at SpringHill Suites by Marriott Sioux Falls enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Breakfast included

Clubhouse Hotel Suites Sioux Falls
2320 South Louise Avenue Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$158 nightly
The price is $174 total per night
$174 total
Dec 30 - Dec 31
Total with taxes and fees
Clubhouse Hotel Suites Sioux Falls features an indoor pool, a children's pool, and a 24-hour gym. There's free parking, as well as a free airport shuttle (available on request). The 24-hour front desk has staff standing by to help with concierge services, luggage storage, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Quality Inn & Suites Sioux Falls South
3216 S Carolyn Ave Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$58 nightly
The price is $66 total per night
$66 total
Dec 28 - Dec 29
Total with taxes and fees
Quality Inn & Suites Sioux Falls South features an indoor pool, free WiFi in public areas, and a business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and luggage storage. Additional amenities include coffee/tea in a common area, a meeting room, and local meal delivery service.
Pool
Breakfast included

TownePlace Suites by Marriott Sioux Falls
4545 W Homefield Dr Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$92 nightly
The price is $103 total per night
$103 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
TownePlace Suites by Marriott Sioux Falls features a full-service spa, an indoor pool, and a 24-hour gym. There's free parking, as well as a free airport shuttle (available on request). The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Other amenities at this spa hotel include free WiFi in public areas, a hot tub, and a 24-hour business center.
Pool
Hot Tub

Hampton Inn Sioux Falls
2417 S Carolyn Ave Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $109 total per night
$109 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
At Hampton Inn Sioux Falls, guests enjoy an indoor pool, a gym, and free WiFi in public areas. There's free parking and a free area shuttle. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub

Comfort Inn & Suites Avera Southwest
3721 W. Avera Drive Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $117 total per night
$117 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests staying at Comfort Inn & Suites Avera Southwest enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, conference space, and a business center.
Pool
Hot Tub

Fairfield Inn & Suites Sioux Falls
4501 W Empire Place Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$83 nightly
The price is $93 total per night
$93 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Fairfield Inn & Suites Sioux Falls, guests enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub

Best Western Empire Towers
4100 W Shirley Place Sioux Falls SD
Free Cancellation
Reserve now, pay when you stay
$72 nightly
The price is $81 total per night
$81 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Best Western Empire Towers features an indoor pool, free WiFi in public areas, and a business center. If you drive, put free parking to good use. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a computer station, express check-out, and free newspapers.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in South Sioux Falls
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Sioux Falls hotels essential information
Accommodation | 370 hotels |
|---|---|
Lowest Price | $66 |
Highest Price | $174 |
Popular hotels | Towneplace Suites Sioux Falls South, Courtyard by Marriott Sioux Falls, Candlewood Suites Sioux Falls by IHG, AmericInn by Wyndham Sioux Falls, La Quinta Inn & Suites by Wyndham Sioux Falls, Staybridge Suites Sioux Falls by IHG, Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG, SpringHill Suites by Marriott Sioux Falls, Clubhouse Hotel Suites Sioux Falls, Quality Inn & Suites Sioux Falls South, TownePlace Suites by Marriott Sioux Falls, Hampton Inn Sioux Falls, Comfort Inn & Suites Avera Southwest, Fairfield Inn & Suites Sioux Falls, Best Western Empire Towers |
Recent Business Hotels Reviews

Days Inn by Wyndham Sioux Falls Empire
5/5 Excellent
"Front desk staff made check in/out easy.
Staff are friendly and courteous.
The room was comfortable and clean."
A verified traveler stayed at Days Inn by Wyndham Sioux Falls Empire
Posted 4 hours ago
More to Explore
- Hotels near Thunder Road Family Fun Park
- Hotels near Denny Sanford Premier Center
- Kid Friendly Hotels in All Saints
- Hotels with Bar in All Saints
- Pet Friendly Hotels in All Saints
- All Saints Hotels
- Hotels with an Indoor Pool in Pettigrew Heights
- Luxury Hotels in Pettigrew Heights
- Pet Friendly Hotels in Pettigrew Heights
- Spa Resorts & in Pettigrew Heights
- Waterpark Hotels & Resorts in Pettigrew Heights
- Hotels near Sioux Empire Fairgrounds
- Hotels near Augustana College
- Hotels near Delbridge Museum of Natural History
- Hotels near University of Sioux Falls
- Apartments in Sioux Falls
- B&B in Sioux Falls
- Cabin Rentals in Sioux Falls
- Hostels in Sioux Falls
- Casino Resorts & in Sioux Falls
- Kid Friendly Hotels in Sioux Falls
- Hotels with Pool in Sioux Falls
- Hotels with Bar in Sioux Falls
- Hotels with Free Airport Shuttle in Sioux Falls
- Hotels with Hot Tubs in Sioux Falls
- Hotels with an Indoor Pool in Sioux Falls
- Luxury Hotels in Sioux Falls
- Pet Friendly Hotels in Sioux Falls
- Waterpark Hotels & Resorts in Sioux Falls
- Sioux Falls Hotels
- Motels in Sioux Falls
- Hotels near Great Plains Zoo
- Hotels with Bar in West 10th Street
- Hotels with Free Breakfast in West 10th Street
- Luxury Hotels in West 10th Street
- Waterpark Hotels & Resorts in West 10th Street
- Hotels near Sanford USD Medical Center
- Hotels with Bar in Folsom's Addition
- Hotels with an Indoor Pool in Folsom's Addition
- Hotels with Kitchenettes in Folsom's Addition
- Pet Friendly Hotels in Folsom's Addition
- Waterpark Hotels & Resorts in Folsom's Addition
- Hotels near Sioux Empire Medical Museum
- Hotels near USS South Dakota Battleship Memorial
- Hotels near Sherman Park
- Hotels near Empire Mall
- Hotels with Pool in McKennan Park
- Spa Resorts & in McKennan Park
- Waterpark Hotels & Resorts in McKennan Park
- Mckennan Park Hotels
- Flights to Sioux Falls
- Flights from Dickinson to Sioux Falls
- Flights from Atlanta to Sioux Falls
- Flights from Austin to Sioux Falls
- Flights from Boston to Sioux Falls
- Flights from Charlotte to Sioux Falls
- Flights from Chicago to Sioux Falls
- Flights from Cincinnati to Sioux Falls
- Flights from Cleveland to Sioux Falls
- Flights from Dallas to Sioux Falls
- Flights from Denver to Sioux Falls
- Flights from Detroit to Sioux Falls
- Flights from Houston to Sioux Falls
- Flights from Indianapolis to Sioux Falls
- Flights from Kansas City to Sioux Falls
- Flights from Los Angeles to Sioux Falls
- Flights from Miami to Sioux Falls
- Flights from Minneapolis - St. Paul to Sioux Falls
- Flights from Nashville to Sioux Falls
- Flights from New York to Sioux Falls
- Flights from Orlando to Sioux Falls
- Flights from Philadelphia to Sioux Falls
- Flights from Phoenix to Sioux Falls
- Flights from Portland to Sioux Falls
- Flights from Salt Lake City to Sioux Falls
- Flights from Seattle to Sioux Falls
- Flights from St. Louis to Sioux Falls
- Flights from Washington to Sioux Falls
- Flights from Hartford to Sioux Falls
- Flights from Sacramento to Sioux Falls
- Flights from Omaha to Sioux Falls
- Flights from Des Moines to Sioux Falls
- Flights from Fort Lauderdale to Sioux Falls
- Flights from Milwaukee to Sioux Falls
- Flights from Madison to Sioux Falls
- Flights from Spokane to Sioux Falls
- Flights from Springfield to Sioux Falls
- Flights from Cedar Rapids - Iowa City to Sioux Falls
- Flights from Colorado Springs to Sioux Falls
- Flights from Tampa to Sioux Falls
- Flights from Grand Rapids to Sioux Falls
- Flights from Bismarck to Sioux Falls
- Flights from Rapid City to Sioux Falls
- Flights from Sioux Falls
- Flights from Bozeman to Sioux Falls
- Flights from Sioux Falls Regional


