Santa Cruz Vacation Homes

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Vacation Homes in Santa Cruz

Don't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Santa Cruz

    Hotel Riu Madeira - All Inclusive

    Hotel Riu Madeira - All Inclusive

    Praia dos Reis Magos Santa Cruz
    $371 nightly
    The price is $391 total per night from Sep 16 to Sep 17
    $391 total
    Sep 16 - Sep 17
    Total with taxes and fees
    9.2/10 Wonderful! (290 reviews)
    Sentido Galosol

    Sentido Galosol

    Rua D. Francisco Santana Santa Cruz Madeira
    $194 nightly
    The price is $207 total per night from Oct 2 to Oct 3
    $207 total
    Oct 2 - Oct 3
    Total with taxes and fees
    Hotel Solar do Bom Jesus

    Hotel Solar do Bom Jesus

    Estrada da Ribeira, 4 Santa Cruz
    $111 nightly
    The price is $120 total per night from Sep 27 to Sep 28
    $120 total
    Sep 27 - Sep 28
    Total with taxes and fees

Santa Cruz Vacation Homes

Book vacation homes in Santa Cruz
Next time you take a group getaway top Santa Cruz, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Santa Cruz vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Santa Cruz vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Santa Cruz; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Santa Cruz rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Santa Cruz is sure to be a winner.

Santa Cruz Vacation Homes essential information

Accommodation
119 Vacation Homes
Lowest Price
$120
Highest Price
$391
Popular accommodation
Quinta do Santo by LovelyStay, GuestReady - Alluring island retreat, Sea View Andrade 3 Bedroom House, Moradia Uriel, Maison, 10 Minutes de Laéroport et Plages. Idéale Vacances Familles et Amis, Charming 2 Bedroom House with Comfortable Living in Camacha, House / Villa - Santa Cruz, Vacation home with fantastic sea views in the first row, Sea House Madeira - Atlantic Ocean