Car Rental with Enterprise, 4500 Campus Dr Ste 100

Reserve your car fast and hassle-free on the free Orbitz app

Free cancellation on most cars, plus option to book now and pay later

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Top deals on 4500 Campus Dr Ste 100 car rental in Irvine

Discover fantastic rates on a huge selection of cars from Enterprise at 4500 Campus Dr Ste 100 in Irvine.

Choose from fun compacts to performance sports cars with Orbitz. We have prices and vehicles to fit your trip perfectly. Book now, pay later, and enjoy special offers!

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