You'll relish every second you spend in intriguing Cayo Largo. The travel specialists at Orbitz can help you get started by linking up amazing-value hotels and airfares.
How do savings of up to sound? Simply choose your preferred airfares, hotels, experiences and rental cars and you'll have some extra change bouncing around in your pockets!
On top of that, you'll be excited to hear that you can pick from 500 airline partners and more than 500,000 accommodations across the globe.
With unlimited options to pick from, our packages will help you design that vacation you've long dreamed about.
Ready to cross Cayo Largo off your world map?
Airports. They can be a bit of a hassle, but traveling would definitely be a lot harder without them! The closest to Cayo Largo is Vilo Acuna Airport (CYO). It's located 5 miles from the downtown area.
Dusted off your passport, booked your big adventure but now you can't go? No need to worry — we make canceling simple and straightforward by not requesting a fee.^ Act promptly and your selected hotel and airline might do the same!
