Buffalo Vacation Homes

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Vacation Homes in Buffalo

Don't see what you're looking for?
See all available properties in Buffalo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Buffalo

    Mardi Gras Casino & Resort

    Mardi Gras Casino & Resort

    #1 Greyhound Drive, Cross Lanes, WV
    $109 nightly
    The price is $123 total per night from Jul 1 to Jul 2
    $123 total
    Jul 1 - Jul 2
    Total includes taxes and fees
    8.2/10 Very Good! (1,406 reviews)
    Wyndham Garden Cross Lanes Charleston

    Wyndham Garden Cross Lanes Charleston

    102 Racer Dr, Cross Lanes, WV
    $107 nightly
    The price is $120 total per night from Jun 8 to Jun 9
    $120 total
    Jun 8 - Jun 9
    Total includes taxes and fees
    7.2/10 Good! (1,001 reviews)
    Quality Inn

    Quality Inn

    577 State Route 7 N, Gallipolis, OH
    $99 nightly
    The price is $109 total per night from Jun 9 to Jun 10
    $109 total
    Jun 9 - Jun 10
    Total includes taxes and fees
    7.6/10 Good! (1,002 reviews)

Buffalo Vacation Homes

Book vacation homes in Buffalo
Next time you take a group getaway top Buffalo, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Buffalo vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Buffalo vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Buffalo; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Buffalo rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Buffalo is sure to be a winner.

Buffalo Vacation Homes essential information

Accommodation
30 Vacation Homes
Lowest Price
$109
Highest Price
$318
Popular accommodation
Ohio River Manor House
Experience the peace and quiet of a country residence!, Quiet and cozy new townhome minutes from the mall exit., Hidden Treasure - WV, “our little French connection” Gallipolis No cleaning fee and Taxes all include, Calm and cozy WV home conveniently located., “our little checkered past” Gallipolis No cleaning fee and no Taxes all include., Spacious 3-bedroom home, off I-64 & 35, sleeps 11, Gallipolis along the river. No cleaning fee and no Taxes., “our little retro scene” No cleaning fee and no Taxes all include.