San Francisco Vacation Homes

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Featured Vacation Homes in San Francisco

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in San Francisco

    Holiday Inn Golden Gateway, an IHG Hotel

    Holiday Inn Golden Gateway, an IHG Hotel

    1500 Van Ness Ave, San Francisco, CA
    The price is $130 per night from Jun 16 to Jun 17
    $130
    per night
    Jun 16 - Jun 17
    8.6/10 Excellent! (2,582 reviews)
    Hotel Riu Plaza Fisherman's Wharf

    Hotel Riu Plaza Fisherman's Wharf

    2500 Mason St, San Francisco, CA
    The price is $145 per night from May 31 to Jun 1
    $145
    per night
    May 31 - Jun 1
    8.6/10 Excellent! (6,207 reviews)
    Handlery Union Square Hotel

    Handlery Union Square Hotel

    351 Geary St, San Francisco, CA
    The price is $139 per night from May 30 to May 31
    $139
    per night
    May 30 - May 31
    8.6/10 Excellent! (1,895 reviews)

San Francisco Vacation Homes

Book vacation homes in San Francisco
Next time you take a group getaway top San Francisco, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of San Francisco vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every San Francisco vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in San Francisco; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a San Francisco rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to San Francisco is sure to be a winner.

San Francisco Vacation Homes essential information

Accommodation
475 Vacation Homes
Lowest Price
$100
Highest Price
$300
Popular accommodation
Pacific Heights Victorian Garden Bedroom & Private Bathroom, Vintage San Francisco Bay Area Home, Contemporary 3bedrooms 2bathrooms in private top floor in very safe neighborhood, Pacific Heights Victorian Home Bedroom and Bathroom , Private Garden Room in Victorian Home!, 3BD House/4 Beds Near Golden Gate Park !, Charming and Cozy Room in Downtown, Pacific Heights Elegant two room suite with bathrooms, 3 Bedroom House, Walking Distance to BART, Attached Garage, Game Room, and Views