Cheap flights from MDT to DSM (Harrisburg Intl. to Des Moines Intl.)

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Cheap Flights from MDT to DSM starting at $113 One Way, $235 Round Trip

Prices starting at $235 for return flights and $113 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jun 5 - Wed, Jun 12
MDT
Harrisburg
DSM
Des Moines
$235 Roundtrip, found 1 day ago
$235
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jun 5 from Harrisburg to Des Moines, returning Wed, Jun 12, priced at $235 found 1 day ago
Wed, Apr 24 - Tue, May 7
MDT
Harrisburg
DSM
Des Moines
$266 Roundtrip, found 3 days ago
$266
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Apr 24 from Harrisburg to Des Moines, returning Tue, May 7, priced at $266 found 3 days ago
Wed, Apr 24 - Tue, May 7
MDT
Harrisburg
DSM
Des Moines
$268 Roundtrip, found 3 days ago
$268
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Apr 24 from Harrisburg to Des Moines, returning Tue, May 7, priced at $268 found 3 days ago
Wed, Jun 5 - Wed, Jun 12
MDT
Harrisburg
DSM
Des Moines
$300 Roundtrip, found 1 day ago
$300
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jun 5 from Harrisburg to Des Moines, returning Wed, Jun 12, priced at $300 found 1 day ago
Wed, Jun 5 - Wed, Jun 12
MDT
Harrisburg
DSM
Des Moines
$305 Roundtrip, found 1 day ago
$305
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jun 5 from Harrisburg to Des Moines, returning Wed, Jun 12, priced at $305 found 1 day ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
The price is $63 per night from Apr 21 to Apr 22
$63
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,107 reviews)
"It was close to the airport and the shuttle to and from the airport."

Reviewed on Apr 19, 2024

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport
Hampton Inn Des Moines-Airport
2.5 out of 5
5001 Fleur Dr, Des Moines, IA
The price is $120 per night from May 5 to May 6
$120
per night
May 5 - May 6
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (1,002 reviews)
"Disappointed that I was charged $50 for parking to fly."

Reviewed on Apr 18, 2024

Hampton Inn Des Moines-Airport
AmericInn by Wyndham Des Moines Airport
AmericInn by Wyndham Des Moines Airport
2.5 out of 5
1920 Hackley Ave, Des Moines, IA
The price is $68 per night from Apr 22 to Apr 23
$68
per night
Apr 22 - Apr 23
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.6/10 Good! (875 reviews)
"Initially we were at room 124 where the carpet was not cleaned, bathroom door did not close properly and the toilet seat was found to be shaky. It would be good if carpets and curtains were replaced."

Reviewed on Apr 16, 2024

AmericInn by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
The price is $86 per night from Apr 21 to Apr 22
$86
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.8/10 Excellent! (1,104 reviews)
"Got an upgrade for thee same price and loved it. Will definitely be back soon. The cottages were very nice and roomy as well."

Reviewed on Apr 17, 2024

Stoney Creek Hotel Des Moines - Johnston
Surety Hotel
Surety Hotel
4 out of 5
206 6th Ave., Des Moines, IA
The price is $118 per night from May 5 to May 6
$118
per night
May 5 - May 6
Stay at this 4-star hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast. Our guests praise the restaurant and the bar in our reviews. Popular ...
9.2/10 Wonderful! (627 reviews)
Nice space
"Nice bathroom and toiletries, cool space, comfy bed. Street parking was fine and saved me money."

Reviewed on Apr 16, 2024

Surety Hotel
Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton
4.5 out of 5
1000 Walnut St, Des Moines, IA
The price is $138 per night from May 5 to May 6
$138
per night
May 5 - May 6
Stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast, and room service. Our guests praise the restaurant and the helpful staff in our reviews. ...
9.4/10 Exceptional! (678 reviews)
"Enjoyed my stay and will book this hotel again, valet was amazing."

Reviewed on Apr 17, 2024

Hotel Fort Des Moines, Curio Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
The price is $63 per night from Apr 21 to Apr 22
$63
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,107 reviews)
"It was close to the airport and the shuttle to and from the airport."

Reviewed on Apr 19, 2024

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport
Quality Inn & Suites Des Moines Airport
2.5 out of 5
5231 Fleur Dr, Des Moines, IA
The price is $67 per night from Apr 30 to May 1
$67
per night
Apr 30 - May 1
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7/10 Good! (764 reviews)
"Construction on road made it touchy. No motel’s fault. Girl at desk was very patient and helpful. Car Play on car map declared the property “permanently closed “ which was remedied by Choice Hotel call. Must say seeing that, was very disconcerting. It was open after their checking for me. Thank ..."

Reviewed on Apr 16, 2024

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport
Hampton Inn Des Moines-Airport
2.5 out of 5
5001 Fleur Dr, Des Moines, IA
The price is $120 per night from May 5 to May 6
$120
per night
May 5 - May 6
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (1,002 reviews)
"Disappointed that I was charged $50 for parking to fly."

Reviewed on Apr 18, 2024

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Days Inn by Wyndham West Des Moines
Days Inn by Wyndham West Des Moines
2 out of 5
1258 8th St, West Des Moines, IA
The price is $45 per night from May 12 to May 13
$45
per night
May 12 - May 13
Stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
5.8/10 (1,005 reviews)
It is what it is.
"Room smelled like an old unfinished basement. Like, a mildew smell. The hallway smelled like every type of air freshener, from a glade plug-in, to a urinal cake. The pool and pool room need a lot of TLC. It's functional, but not presentable. Continental breakfast is what it is, and it's not much. ..."

Reviewed on Apr 13, 2024

Days Inn by Wyndham West Des Moines
Motel 6 West Des Moines, IA
Motel 6 West Des Moines, IA
2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
The price is $62 per night from Apr 21 to Apr 22
$62
per night
Apr 21 - Apr 22
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
6.8/10 (1,001 reviews)
"👌"

Reviewed on Apr 16, 2024

Motel 6 West Des Moines, IA
Cozy Rest Motel
Cozy Rest Motel
2 out of 5
2316 Southeast 14th Street, Des Moines, IA
The price is $62 per night from May 13 to May 14
$62
per night
May 13 - May 14
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (549 reviews)
"Had a nice stay. The facility is close to a busy road so I heard the traffic very early but that isn't the facilities fault. Clean and the staff was helpful and nice"

Reviewed on Apr 6, 2024

Cozy Rest Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
3 out of 5
5000 Merle Hay Rd, Urbandale, IA
The price is $85 per night from May 5 to May 6
$85
per night
May 5 - May 6
Stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
6.4/10 (1,003 reviews)

Families like: Indoor pools, waterpark, game room, extra beds/cribs

Travelers say...
"Good"

Reviewed on Apr 18, 2024

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Wildwood Lodge
Wildwood Lodge
3 out of 5
11431 Forest Ave, Clive, IA
The price is $103 per night from May 5 to May 6
$103
per night
May 5 - May 6
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
9.4/10 Exceptional! (1,355 reviews)

Families like: Indoor pools, free breakfast for the whole family, laundry

Travelers say...
"Really impressed with the hotel. Very comfortable, friendly staff, clean room, nice shower! Will be making this our regular Des Moines stop!!"

Reviewed on Apr 15, 2024

Wildwood Lodge
Baymont by Wyndham Des Moines Airport
Baymont by Wyndham Des Moines Airport
2.5 out of 5
6221 Willow Creek Ave, Des Moines, IA
The price is $98 per night from Apr 21 to Apr 22
$98
per night
Apr 21 - Apr 22
Stay at this golf hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular ...
9.4/10 Exceptional! (1,001 reviews)

Families like: Indoor pools, game room, extra beds/cribs, games and toys

Travelers say...
"Although an older property, the Baymont was clean and very well maintained. Our room had been updated and was very spacious and comfortable. The breakfast was particularly tasty. All the food was hot."

Reviewed on Apr 16, 2024

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Map To Nearby Hotels

MDT to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago

Frequently asked questions

Am I able to catch a flight from Harrisburg, PA Airport (MDT-Harrisburg Intl.) to Des Moines, IA Airport (DSM-Des Moines Intl.) now?
The Covid-19 Travel Advisor can answer all your questions about travel restrictions and quarantine when flying from Harrisburg, PA Airport (MDT-Harrisburg Intl.) to Des Moines, IA Airport (DSM-Des Moines Intl.).
Are there non-stop flights from Harrisburg Intl. Airport to Des Moines Intl. Airport?
You’ll have to swap planes if you’re wanting to get from Harrisburg Intl. Airport to Des Moines Intl. Airport. A range of companies operate on this route with just one stopover, including American Airlines, Delta and United Airlines.
What is the shortest flight from Harrisburg Intl. Airport to Des Moines Intl. Airport?
Order an in-flight wine and sink into your seat with an interesting movie or book. With the journey from Paxinos to Downtown Des Moines taking 4 hours and 21 minutes, you’ll have plenty of time to kick back and enjoy the experience.
How many hours flight from Harrisburg Intl. Airport (MDT) to DSM?
Typically, it takes 4 hours and 26 minutes to travel from MDT to DSM. You’ll be in the air for quite some time, so contemplate bringing plenty of entertainment, like a novel or a podcast.
If I am not able to travel due to COVID-19, can I cancel my flight to Des Moines, IA Airport (DSM-Des Moines Intl.)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Des Moines, IA Airport (DSM-Des Moines Intl.) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Des Moines, IA Airport (DSM-Des Moines Intl.) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Des Moines, IA Airport (DSM-Des Moines Intl.) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to Des Moines Intl. Airport (DSM)?
You won’t be able to find any airlines that operate direct flights between MDT and Des Moines Intl. Airport (DSM). Be organized and reserve a multi-stop or one-stop plane ticket.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.