Selected fares from Columbia to San Diego

Columbia to San Diego Intro 50

Orbitz gives you great deals on your flights from Columbia to San Diego. If you also need a discount car rental or a cheap hotel room after you arrived at your destination, Orbitz has you covered.

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When you book flights from Columbia to San Diego with Orbitz for, you can be assured that you are getting the lowest price possible. Orbitz works constantly with our airline partners to ensure guaranteed low prices on Columbia to San Diego flights for your trip—whether you are traveling for business or for fun with your family.

Enjoy Savings on Last-Minute Flights

If you are looking for a discount price on last-minute flights from Columbia to San Diego, chances are that Orbitz can offer you a deal that will save you lots of money. Whether you just want to get away for the weekend or go on a vacation lasting weeks, Orbitz can help you find the best deals on Columbia to San Diego flights that fit your budget and your itinerary for the perfect trip.

Full-Service Mobile Apps

Need more mobility when it comes to travel planning? Orbitz has easy-to-use mobile apps for iPhone, iPad, and Android, to help the traveler on the go. Not only can use the apps to find huge savings on Columbia to San Diego flights wherever you are, but you can also check out and book discount hotel rooms too. The apps will also keep you up-to-date when it’s time to fly. Get easy access to your itinerary for flights from Columbia to San Diego and review gate and baggage claim details too.

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Save more with San Diego Flight + Hotel packages

Hotels in San Diego

See all 551 Hotels in San Diego
Days Inn San Diego Hotel Circle Near SeaWorld
Days Inn San Diego Hotel Circle Near SeaWorld
543 Hotel Circle S, San Diego
3.0 out of 5.0
3.6 out of 5 (1,015 reviews)

Located in San Diego's Mission Valley corridor just off I-8, this San Diego hotel is a half-mile from 2 shopping centers, and within 5 miles of SeaWorld, downtown, ...

$69

$69
The Sofia Hotel
The Sofia Hotel
150 W Broadway, San Diego
3.5 out of 5.0
4.1 out of 5 (421 reviews)

In the heart of downtown San Diego, this historic boutique hotel is 2 blocks from Horton Plaza, 4 blocks from the Gaslamp Quarter, and 6 blocks from the San ...

$113

$113
Carlsbad By The Sea Resort
Carlsbad By The Sea Resort
850 Palomar Airport Road, Carlsbad
3.0 out of 5.0
3.8 out of 5 (212 reviews)

Guests at Carlsbad By the Sea Resort can cross the street to shop at Barney’s New York and Calvin Klein, just 2 of the more than 90 stores at Carlsbad Premium ...

$104

$104
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego
4.0 out of 5.0
4.3 out of 5 (276 reviews)

This expansive highrise hotel towers over San Diego Bay next to the Seaport Village retail complex, 1 block from the convention center, and 2 blocks from the ...

$219

$219
Best Western Seven Seas
Best Western Seven Seas
411 Hotel Circle South, San Diego
3.0 out of 5.0
3.6 out of 5 (271 reviews)

Adjacent to I-8, this budget-friendly hotel is within 6 miles of 2 sports stadiums, the Gaslamp Quarter, the convention center, the San Diego Zoo, SeaWorld, ...

$75

$75
Hilton San Diego Bayfront
Hilton San Diego Bayfront
1 Park Blvd, San Diego
4.0 out of 5.0
4.1 out of 5 (324 reviews)

Rising 30 stories above San Diego Bay, this modern Hilton is adjacent to the San Diego Convention Center, across from Petco Park, and 3 blocks from the Gaslamp ...

$173

$173
Mission Valley Resort
Mission Valley Resort
875 Hotel Cir South, San Diego
2.5 out of 5.0
2.3 out of 5 (23 reviews)

Comprising 8 buildings in a tropical setting near the foothills of Mission Valley, and convenient to I-8, this resort is 2 miles from Old Town and 4 miles from ...

$57

$57
Wyndham San Diego Bayside
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego
3.5 out of 5.0
3.7 out of 5 (308 reviews)

Just west of the downtown core, this San Diego hotel is across the street from the cruise ship terminal, Coronado ferry, and the Maritime Museum. The Gaslamp ...

$135

$135
Sheraton San Diego Hotel and Marina
Sheraton San Diego Hotel and Marina
1380 Harbor Island Dr, San Diego
4.0 out of 5.0
3.9 out of 5 (471 reviews)

Situated on San Diego Bay with its own marina, the Sheraton San Diego Hotel and Marina is 1 mile (1.6 km) away from San Diego International Airport, and just ...

$139

$139
The Dana on Mission Bay, BW Premier Collection
The Dana on Mission Bay, BW Premier Collection
1710 W Mission Bay Dr, San Diego
3.5 out of 5.0
3.9 out of 5 (494 reviews)

Adjacent to San Diego's Mission Bay, this 13-acre hotel is within 2 miles of SeaWorld and Mission Beach, and 6 miles of the San Diego Zoo.

$139

$139

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 48 hours. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.