Selected fares from Panama City to San Diego

Panama City to San Diego Intro 14

Orbitz combines guaranteed low prices with cutting-edge mobile tools for travel from Panama City to San Diego to give you a travel experience that is second to none.

Bargain Travel at Your Fingertips

Orbitz provides the cheapest fares from Panama City to San Diego. When reserving your flight you can mix and match a range of low cost airlines for you departing and returning domestic or international flights. This way you can travel on a budget while selecting the flights that suit your schedule.

Modern Tools for Fast-Paced Travel

Orbitz makes use of the latest technology to ensure that you are always kept up-to-date on the status of your Panama City to San Diego flights. Through easy-to-use mobile Android and iPhone apps you can book low cost flights from Panama City to San Diego and choose a range of cheap hotels to stay in.

Enjoy Stress-Free Travel with Flight Alerts

Once you have booked your flights from Panama City to San Diego on Orbitz you will always be kept informed of any changes to your flight. When you opt into Orbitz’s free email and SMS alerts on your Panama City to San Diego flights you can ask Orbitz to send the flight details to up to 6 other contacts, so keeping your family and business team informed is a cinch.

Frequent Flyer Program

For loyal Orbitz customers who fly from Panama City to San Diego the chance to join our frequent flyer program is an added bonus. Simply log-on to your online account and input your frequent flyer number for future flights.

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Save more with San Diego Flight + Hotel packages

Hotels in San Diego

See all 551 Hotels in San Diego
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
1 Market Pl, San Diego
4.0 out of 5.0
4.3 out of 5 (276 reviews)

This expansive highrise hotel towers over San Diego Bay next to the Seaport Village retail complex, 1 block from the convention center, and 2 blocks from the ...

$219

$219
Days Inn San Diego Hotel Circle Near SeaWorld
Days Inn San Diego Hotel Circle Near SeaWorld
543 Hotel Circle S, San Diego
3.0 out of 5.0
3.6 out of 5 (1,017 reviews)

Located in San Diego's Mission Valley corridor just off I-8, this San Diego hotel is a half-mile from 2 shopping centers, and within 5 miles of SeaWorld, downtown, ...

$69

$69
The Sofia Hotel
The Sofia Hotel
150 W Broadway, San Diego
3.5 out of 5.0
4.1 out of 5 (421 reviews)

In the heart of downtown San Diego, this historic boutique hotel is 2 blocks from Horton Plaza, 4 blocks from the Gaslamp Quarter, and 6 blocks from the San ...

$113

$113
Carlsbad By The Sea Resort
Carlsbad By The Sea Resort
850 Palomar Airport Road, Carlsbad
3.0 out of 5.0
3.8 out of 5 (212 reviews)

Guests at Carlsbad By the Sea Resort can cross the street to shop at Barney’s New York and Calvin Klein, just 2 of the more than 90 stores at Carlsbad Premium ...

$104

$104
Best Western Seven Seas
Best Western Seven Seas
411 Hotel Circle South, San Diego
3.0 out of 5.0
3.6 out of 5 (271 reviews)

Adjacent to I-8, this budget-friendly hotel is within 6 miles of 2 sports stadiums, the Gaslamp Quarter, the convention center, the San Diego Zoo, SeaWorld, ...

$75

$75
Wyndham San Diego Bayside
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego
3.5 out of 5.0
3.7 out of 5 (308 reviews)

Just west of the downtown core, this San Diego hotel is across the street from the cruise ship terminal, Coronado ferry, and the Maritime Museum. The Gaslamp ...

$135

$135
Mission Valley Resort
Mission Valley Resort
875 Hotel Cir South, San Diego
2.5 out of 5.0
2.3 out of 5 (23 reviews)

Comprising 8 buildings in a tropical setting near the foothills of Mission Valley, and convenient to I-8, this resort is 2 miles from Old Town and 4 miles from ...

$57

$57
The Dana on Mission Bay, BW Premier Collection
The Dana on Mission Bay, BW Premier Collection
1710 W Mission Bay Dr, San Diego
3.5 out of 5.0
3.9 out of 5 (496 reviews)

Adjacent to San Diego's Mission Bay, this 13-acre hotel is within 2 miles of SeaWorld and Mission Beach, and 6 miles of the San Diego Zoo.

$139

$139
Sheraton San Diego Hotel and Marina
Sheraton San Diego Hotel and Marina
1380 Harbor Island Dr, San Diego
4.0 out of 5.0
3.9 out of 5 (471 reviews)

Situated on San Diego Bay with its own marina, the Sheraton San Diego Hotel and Marina is 1 mile (1.6 km) away from San Diego International Airport, and just ...

$139

$139
Hilton San Diego Bayfront
Hilton San Diego Bayfront
1 Park Blvd, San Diego
4.0 out of 5.0
4.1 out of 5 (324 reviews)

Rising 30 stories above San Diego Bay, this modern Hilton is adjacent to the San Diego Convention Center, across from Petco Park, and 3 blocks from the Gaslamp ...

$173

$173

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 48 hours. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.