Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Hotels in Seneca

See all 102 Hotels in Seneca
Quality Inn Seneca / Clemson

Quality Inn Seneca / Clemson

226 Hi Tech Rd, Seneca
    2.5 out of 5.0
     
     

    Situated in Seneca, this hotel is within 9 mi (15 km) of Little John Coliseum, Clemson University, and Memorial Stadium. Brooks Center for the Performing Arts ...

    Quality Inn Seneca / Clemson$75

    Quality Inn Seneca / Clemson$75
    Hampton Inn & Suites Seneca-Clemson Area

    Hampton Inn & Suites Seneca-Clemson Area

    1011 East North 1st Street, Seneca
      2.5 out of 5.0
       
       
      4.7 out of 5 (6 reviews)

      Situated in Seneca, this hotel is within 9 mi (15 km) of Little John Coliseum, Clemson University, and Memorial Stadium. Brooks Center for the Performing Arts ...

      Hampton Inn & Suites Seneca-Clemson Area$101

      Hampton Inn & Suites Seneca-Clemson Area$101
      Days Inn Seneca Clemson SC

      Days Inn Seneca Clemson SC

      11015 N Radio Station Rd, Seneca
        2.0 out of 5.0
         
         
        3.0 out of 5 (3 reviews)

        Situated in Seneca, this motel is within 12 mi (20 km) of Little John Coliseum, Clemson University, and Memorial Stadium. Brooks Center for the Performing Arts ...

        Days Inn Seneca Clemson SC$59

        Days Inn Seneca Clemson SC$59
        Large Quiet Cove on Lake Keowee

        Large Quiet Cove on Lake Keowee

        , Seneca
           
           

          Situated on a lake, this vacation home is in the same region as Little John Coliseum, Clemson University, and Memorial Stadium. Regional attractions also include ...

          Minutes From Clemson, Lake Hartwell, Local Dining, Shopping & More!

          Minutes From Clemson, Lake Hartwell, Local Dining, Shopping & More!

          , Seneca
             
             

            Situated in Seneca, this property is in the same area as Little John Coliseum, Clemson University, and Memorial Stadium. Area attractions also include Walker ...

            Beautiful Lake Keowee Getaway In The Heart Of South Carolina's Oconee County!

            Beautiful Lake Keowee Getaway In The Heart Of South Carolina's Oconee County!

            , Seneca
               
               

              Situated in the city center, this property is in the same area as Little John Coliseum. Regional attractions also include Clemson University and Memorial ...

              Keowee Waterfront W/private Dock Close to Marina, 7 mi to Clemson's Death Valley

              Keowee Waterfront W/private Dock Close to Marina, 7 mi to Clemson's Death Valley

              , Seneca
                 
                 

                Situated on a lake, this vacation home is in the same region as Little John Coliseum, Clemson University, and Memorial Stadium. Regional attractions also include ...

                Clemson University's James F. Martin Inn

                Clemson University's James F. Martin Inn

                240 Madren Center Drive, Clemson
                  3.0 out of 5.0
                   
                   
                  4.3 out of 5 (7 reviews)

                  Situated on the waterfront, this hotel is 0.1 mi (0.2 km) from Walker Golf Course and 1.3 mi (2.1 km) from Clemson University. Brooks Center for the Performing ...

                  Clemson University's James F. Martin Inn$116

                  Clemson University's James F. Martin Inn$116
                  Baymont Inn and Suites Anderson Clemson

                  Baymont Inn and Suites Anderson Clemson

                  128 Interstate Blvd, Anderson
                    2.5 out of 5.0
                     
                     
                    3.8 out of 5 (11 reviews)

                    Situated in Anderson, this hotel is 4.1 mi (6.6 km) from Anderson Mall and within 12 mi (20 km) of Anderson County Museum and South Carolina Botanical ...

                    Baymont Inn and Suites Anderson Clemson$65

                    Baymont Inn and Suites Anderson Clemson$65
                    Quality Inn

                    Quality Inn

                    3430 Clemson Blvd, Anderson
                      2.0 out of 5.0
                       
                       
                      3.4 out of 5 (50 reviews)

                      Situated on the Strip, this hotel is 0.8 mi (1.3 km) from Anderson Mall and within 6 mi (10 km) of Anderson County Museum and Anderson University. NewSpring ...

                      Quality Inn$60

                      Quality Inn$60
                      Map

                      Recently Booked Hotels in Seneca

                      Quality Inn Seneca / Clemson
                      2.5 out of 5.0
                      Last booking: 46 hours ago
                      Hotels in Seneca

                      Get busy relaxing in Seneca! With 73 hotels, Orbitz makes it easy to find a place, get settled and start exploring. Our Seneca hotels also rate highly for Location and Hotel Staff, helping ensure your stay is comfortable. You'll be out sightseeing at Memorial Stadium (Death Valley), South Carolina Botanical Garden, Clemson Memorial Stadium and Doug Kingsmore Stadium in no time.


                      Best times to visit Seneca

                      If you're planning a trip to Seneca, consider visiting in March, January and February. Orbitz offers great deals 365 days a year, but during these months, you'll save the most — 39%, 38% and 37%, respectively.


                      Where to shop in Seneca

                      Want a whole new wardrobe? The shops in Oconee Square Shopping Center and the clothes at Belk won't disappoint. You can pick up sparkling accessories for any occasion at Brock's Seneca Jewelers.

                      If wearable tech is more your speed, check out the gadgets and accessories at Kmart.


                      Things to do in Seneca

                      It's hard to get bored while enjoying some hearty snacks and watching athletes compete. Take it all in at Seneca's Memorial Stadium (Death Valley), Clemson Memorial Stadium and Doug Kingsmore Stadium.

                      If you're looking for a relaxing way to have fun in Seneca, you can always head to Simplicity Salon & Spa and indulge in some serious pampering.


                      Things to do in Seneca

                      It's hard to get bored while enjoying some hearty snacks and watching athletes compete. Take it all in at Seneca's Memorial Stadium (Death Valley), Clemson Memorial Stadium and Doug Kingsmore Stadium.

                      If you're looking for a relaxing way to have fun in Seneca, you can always head to Simplicity Salon & Spa and indulge in some serious pampering.


                      Where to shop in Seneca

                      Want a whole new wardrobe? The shops in Oconee Square Shopping Center and the clothes at Belk won't disappoint. You can pick up sparkling accessories for any occasion at Brock's Seneca Jewelers.

                      If wearable tech is more your speed, check out the gadgets and accessories at Kmart.


                      Arts and culture in Seneca

                      Some of Seneca's popular attractions are steeped in culture. Soak it in at Fort Hill( Calhoun & Clemson Mansion) and Lunney Museum or Clemson Hair Art while enjoying a quiet afternoon.

                      Entertainment and education abound at Booksmith and Pendleton District Commission, where you can catch up on history, fiction and current events.

                      Greenville Hospital System University draws students and alums alike to its campus and its atmosphere of higher education.


                      Where to eat in Seneca

                      Few experiences are as satisfying as a good, hearty meal. Luckily, that's easy to find in Seneca — just grab a table at Schlotzsky's, Pizza Hut, Los Amigos Mexican Restaurant and Zaxby's and tuck in.


                      Nightlife in Seneca

                      After the sun goes down, shake a tail feather or grab a drink in Seneca. Blue Heron Restaurant and Sushi Bar and Vapehalla are good places to belly up to the bar and order a cold drink or chat with the locals — or both.


                      Arts and culture in Seneca

                      Some of Seneca's popular attractions are steeped in culture. Soak it in at Fort Hill( Calhoun & Clemson Mansion) and Lunney Museum or Clemson Hair Art while enjoying a quiet afternoon.

                      Entertainment and education abound at Booksmith and Pendleton District Commission, where you can catch up on history, fiction and current events.

                      Greenville Hospital System University draws students and alums alike to its campus and its atmosphere of higher education.


                      * Prices reflect the lowest "base rate" found over the next 30 days. Rates are subject to change and may not include taxes and fees, hotel service charges, extra person charges, or incidentals, such as room service. All rates are displayed in USD unless otherwise noted. Converted rates are provided for your convenience. They are based on today's exchange rate, but the hotel will charge you in the local currency.