Hotels in Santee

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Apr 24 - Apr 25
Tonight
Check prices in Santee for tonight, Apr 24 - Apr 25
Apr 25 - Apr 26
Tomorrow night
Check prices in Santee for tomorrow night, Apr 25 - Apr 26

Top Rated Santee Hotels

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.26 mi from city center
The price is $75 per night
$75
per night
Apr 28 - Apr 29
At Baymont by Wyndham Santee, guests have access to free WiFi in public areas, coffee in a common area, and express check-in. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help with concierge services, and answer any questions about the area. Additional amenities include express check-out and a vending machine.
Pet friendly
Breakfast included
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.26 mi from city center
The price is $123 per night
$123
per night
May 5 - May 6
At Tru By Hilton Santee, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. This hotel also has a 24-hour business center.
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
8929 Old Number Six Highway, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.14 mi from city center
The price is $59 per night
$59
per night
May 2 - May 3
Quality Inn & Suites features free WiFi in public areas, a seasonal outdoor pool, and microwave in a common area. If you drive, put free parking to good use. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations. Additional amenities include a refrigerator in a common area, a computer station, and laundry facilities.
Pet friendly
Breakfast included
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.17 mi from city center
The price is $133 per night
$133
per night
May 19 - May 20
Renovated in 2023, Comfort Inn & Suites Santee offers a gym, free WiFi in public areas, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Breakfast included
Pool
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.62 mi from city center
The price is $156 per night
$156
per night
Apr 30 - May 1
Guests staying at Fairfield Inn & Suites by Marriott Santee enjoy an outdoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pet friendly
Breakfast included
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.59 mi from city center
The price is $148 per night
$148
per night
May 20 - May 21
At Hampton Inn Santee-I-95, guests have access to a 24-hour gym, free WiFi in public areas, and conference space. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and free newspapers.
Pet friendly
Breakfast included
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.73 mi from city center
The price is $60 per night
$60
per night
May 19 - May 20
Travelodge by Wyndham Santee features free WiFi in public areas, a business center, and a seasonal outdoor pool. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with tours/tickets and securing valuables. Additional amenities include coffee/tea in a common area, a vending machine, and an ATM.
Holiday Inn Santee, an IHG Hotel

Holiday Inn Santee, an IHG Hotel

3 out of 5
139 Bradford Blvd, Santee, SC
Free Cancellation
0.17 mi from city center
The price is $159 per night
$159
per night
May 1 - May 2
At Holiday Inn Santee, an IHG Hotel, guests enjoy an indoor pool, a gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98, Santee, SC
0.56 mi from city center
The price is $136 per night
$136
per night
May 7 - May 8
Guests staying at Best Western Plus Santee Inn enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. Additional amenities include conference space, a business center, and free newspapers.
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.17 mi from city center
The price is $70 per night
$70
per night
Apr 25 - Apr 26
Red Roof Inn Santee features free WiFi in public areas, coffee in a common area, and express check-out. If you drive, put free parking to good use. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a vending machine.
Pet friendly
Breakfast included
Super 8 by Wyndham Santee

Super 8 by Wyndham Santee

2 out of 5
9125 Old Highway 6, Santee, SC
Free Cancellation
Reserve now, pay when you stay
0.78 mi from city center
The price is $75 per night
$75
per night
Apr 25 - Apr 26
Guests of Super 8 by Wyndham Santee enjoy access to free WiFi in public areas, meeting rooms, and a business center. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Other amenities at this golf motel include a seasonal outdoor pool, express check-in, and express check-out.
Executive 2 BR/2 BA Lakefront Corner Suite Condo

Executive 2 BR/2 BA Lakefront Corner Suite Condo

1.36 mi from city center
Guests staying at this condo can enjoy an outdoor pool, barbecue grills, and a garden.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Santee hotels options

    Baymont by Wyndham Santee

    Baymont by Wyndham Santee

    249 Britain Street, Santee, SC
    The price is $75 per night from Apr 28 to Apr 29
    $75
    per night
    Apr 28 - Apr 29
    7.8/10 Good! (1,318 reviews)
    Red Roof Inn Santee

    Red Roof Inn Santee

    9091 Old Hwy 6, Santee, SC
    The price is $70 per night from Apr 25 to Apr 26
    $70
    per night
    Apr 25 - Apr 26
    6.4/10 (551 reviews)
    Travelodge by Wyndham Santee

    Travelodge by Wyndham Santee

    9117 Old Number Six Hwy, Santee, SC
    The price is $60 per night from May 19 to May 20
    $60
    per night
    May 19 - May 20
    6.8/10 (473 reviews)
    Super 8 by Wyndham Santee

    Super 8 by Wyndham Santee

    9125 Old Highway 6, Santee, SC
    The price is $75 per night from Apr 25 to Apr 26
    $75
    per night
    Apr 25 - Apr 26
    6.6/10 (390 reviews)
    Econo Lodge

    Econo Lodge

    9112 Old 6 Highway, Santee, SC
    The price is $63 per night from May 7 to May 8
    $63
    per night
    May 7 - May 8
    6.2/10 (301 reviews)
    Comfort Inn & Suites Santee

    Comfort Inn & Suites Santee

    221 Britain St, Santee, SC
    The price is $133 per night from May 19 to May 20
    $133
    per night
    May 19 - May 20
    7.8/10 Good! (834 reviews)

Where is a good place to stay in Santee?

What are the best family-friendly hotels in Santee?

Check out these hotels for your family's stay in Santee. Comfort Inn & Suites Santee is a hotel offering free parking, free buffet breakfast, and laundry facilities. You and your family can also consider Fairfield Inn & Suites by Marriott Santee, a hotel offering an outdoor pool, free parking, and free breakfast.

What are the best hotels in central Santee?

Here are some of the most popular hotels in the center of Santee:

While you're enjoying local activities like golfing, take some time to check out the restaurants in family-friendly Santee. Close to central Santee, you'll find interesting places to visit like Santee Cooper Country Club.

What are some of the best hotels near Santee State Park?

Get some fresh air at this natural setting, which is 2.7 mi from the heart of Santee. You'll find 20 hotels within 5 miles of Santee State Park, giving you plenty of options to choose from including:

Santee hotels essential information

Accommodation
204 hotels
Lowest Price
$59
Highest Price
$159
Popular hotels
Baymont by Wyndham Santee, Tru By Hilton Santee, Quality Inn & Suites, Comfort Inn & Suites Santee, Fairfield Inn & Suites by Marriott Santee, Hampton Inn Santee-I-95, Travelodge by Wyndham Santee, Holiday Inn Santee, an IHG Hotel, Best Western Plus Santee Inn, Red Roof Inn Santee, Super 8 by Wyndham Santee, Executive 2 BR/2 BA Lakefront Corner Suite Condo

Recent Reviews

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

5/5 Excellent
"Ok"
A verified traveler stayed at Comfort Inn & Suites Santee
Posted 22 hours ago
Comfort Inn & Suites Santee

Areas Of Santee

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