Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Join Orbitz Rewards
Earn rewards and exclusive perks with Orbitz Rewards, just like that.

Get Insider Pricing
Save up to 50% on select hotels with Insider Prices—it’s easy.

Save on Packages
Up to $536 by booking Flight + Hotel together*

Cape Girardeau Hotels

See all 29 Hotels in Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau
    2.5 out of 5.0
     
     
    3.8 out of 5 (45 reviews)

    Located in the heart of Cape Girardeau, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State ...

    Pear Tree Inn Cape Girardeau Near the Medical Center$70

    Pear Tree Inn Cape Girardeau Near the Medical Center$70
    Drury Plaza Hotel Cape Girardeau Conference Center

    Drury Plaza Hotel Cape Girardeau Conference Center

    3351 Percy Drive, Cape Girardeau
      3.0 out of 5.0
       
       

      Situated in Cape Girardeau, this hotel is 2.2 mi (3.5 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

      Drury Plaza Hotel Cape Girardeau Conference Center$115

      Drury Plaza Hotel Cape Girardeau Conference Center$115
      Pear Tree Inn Cape Girardeau West

      Pear Tree Inn Cape Girardeau West

      103 Cape West Pkwy, Cape Girardeau
        2.5 out of 5.0
         
         
        3.5 out of 5 (6 reviews)

        Located in the heart of Cape Girardeau, this hotel is 2.8 mi (4.4 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State ...

        Pear Tree Inn Cape Girardeau West$70

        Pear Tree Inn Cape Girardeau West$70
        Hampton Inn Cape Girardeau I 55 East

        Hampton Inn Cape Girardeau I 55 East

        207 S Mt Auburn Rd, Cape Girardeau
          2.5 out of 5.0
           
           
          5.0 out of 5 (3 reviews)

          Situated in Cape Girardeau, this hotel is 2.4 mi (3.8 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

          Hampton Inn Cape Girardeau I 55 East$101

          Hampton Inn Cape Girardeau I 55 East$101
          Auburn Place Hotel And Suites

          Auburn Place Hotel And Suites

          3265 William St, Cape Girardeau
            2.5 out of 5.0
             
             
            4.6 out of 5 (35 reviews)

            Situated in Cape Girardeau, this hotel is 2.3 mi (3.7 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

            Auburn Place Hotel And Suites$79

            Auburn Place Hotel And Suites$79
            Holiday Inn Express Hotel & Suites Cape Girardeau I-55

            Holiday Inn Express Hotel & Suites Cape Girardeau I-55

            3253 William Street, Cape Girardeau
              2.5 out of 5.0
               
               
              4.7 out of 5 (26 reviews)

              Situated in a rural location, this hotel is 2.2 mi (3.6 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

              Holiday Inn Express Hotel & Suites Cape Girardeau I-55$109

              Holiday Inn Express Hotel & Suites Cape Girardeau I-55$109
              Town House Inn Cape Giradreau

              Town House Inn Cape Giradreau

              505 North Kingshighway Street, Cape Girardeau
                2.5 out of 5.0
                 
                 

                Situated in Cape Girardeau, this motel is within 3 mi (5 km) of Cape Splash Family Aquatic Center, Southeast Missouri State University, and Isle Casino Cape ...

                Town House Inn Cape Giradreau$54

                Town House Inn Cape Giradreau$54
                Drury Inn & Suites Cape Girardeau

                Drury Inn & Suites Cape Girardeau

                3303 Campster Drive, Cape Girardeau
                  3.0 out of 5.0
                   
                   
                  4.5 out of 5 (12 reviews)

                  Located in the heart of Cape Girardeau, this hotel is 2.7 mi (4.4 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State ...

                  Drury Inn & Suites Cape Girardeau$95

                  Drury Inn & Suites Cape Girardeau$95
                  Candlewood Suites Cape Girardeau

                  Candlewood Suites Cape Girardeau

                  485 S Mount Auburn Rd, Cape Girardeau
                    2.5 out of 5.0
                     
                     
                    4.5 out of 5 (11 reviews)

                    Situated in Cape Girardeau, this hotel is 3 mi (4.9 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Southeast Missouri State University ...

                    Candlewood Suites Cape Girardeau$89

                    Candlewood Suites Cape Girardeau$89
                    Americas Best Value Inn Cape Girardeau

                    Americas Best Value Inn Cape Girardeau

                    2011 North Kingshighway, Cape Girardeau
                      2.0 out of 5.0
                       
                       
                      3.1 out of 5 (20 reviews)

                      Situated in Cape Girardeau, this motel is 0.7 mi (1.2 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Lazy L Safari Park and Southeast ...

                      Map

                      *Savings based on all holiday package bookings with Flight + Hotel on Orbitz.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      * Prices reflect the lowest "base rate" found over the next 30 days. Rates are subject to change and may not include taxes and fees, hotel service charges, extra person charges, or incidentals, such as room service. All rates are displayed in USD unless otherwise noted. Converted rates are provided for your convenience. They are based on today's exchange rate, but the hotel will charge you in the local currency.