Book 5 Star Hotels in Cayo Santa Maria

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Featured Cayo Santa Maria 5 Stars Hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best 5 star hotels in Cayo Santa Maria

Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Cayo Santa Maria. After all, treating yourself to the finer things is what vacations are about. 

What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Cayo Santa Maria hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.

What amenities can I expect at a 5 star hotel?
Cayo Santa Maria 5 star hotels and resorts typically offer luxury amenities such as:

  • Gourmet restaurant
  • Full-service fitness center with pool
  • Luxury spa 
  • Welcome gifts upon arrival
  • Top-of-the-line beds and linens 
  • Designer personal care products
  • Premium cable, free Wi-Fi and device docking stations

How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Cayo Santa Maria with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place: 

  • Search hotels by price, ranging from to
  • Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
  • Choose from 4 5 star hotels in Cayo Santa Maria!

Cayo Santa Maria hotels essential information

Accommodation
4 hotels
Lowest Price
Highest Price
Popular hotels
Villa Gaviota Cayo Coco, Grand Memories Santa Maria - All Inclusive, Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive, Hotel Las Salinas Plaza & Spa