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La Crosse Vacations

Your trip

Hotel options

Hotel stay must be within date range of Leave and Return.

Room 1
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Your La Crosse vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for La Crosse vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

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La Crosse Vacation Packages

Hotel only $109

1 GrandStay Residential Suites La Crosse

3 stars
4.2 / 5 37 reviews

525 Front Street North Map

Located in historic downtown La Crosse by the Mississippi River. Our all suite hotel specializes in extended stay and nightly accommodations. While staying with us enjoy our new renovations and FREE Grand Start® Breakfast. We combine all the comforts of home with the... More

Hotel only $66

2 Settle Inn La Crosse

2 stars
3.8 / 5 52 reviews

2110 Rose Street Map

The perfect place to stay while in the La Crosse area. Whether business or leisure, our great amenities package provides luxury at an affordable price. We offer free kickstart breakfast, free high speed wireless intenet, indoor pool and spa, large lobby and 27 inch remote... More

Hotel only $81

3 Holiday Inn Hotel & Suites LA CROSSE

3 stars
3.8 / 5 21 reviews


Relax at La Crosse, Wisconsin Hotel's Downtown Location Positioned near the Mississippi River and across the street from the La Crosse Center, the Holiday Inn® Hotel & Suites La Crosse welcomes visitors with a courteous staff who strive to make their stay more enjoyable.... More

Hotel only $76

4 Best Western Riverfront Hotel Lacrosse WI

3 stars
3.2 / 5 78 reviews

1835 Rose Street Map

Save 5% on your stay

Retreat to this La Crosse, Wisconsin hotel and enjoy comfortable and affordable amenities convenient to the Mississippi River, the Shrine of Our Lady Guadeloupe and the Mississippi Eco-Tour Boat. Property is 100% non-smoking. Welcome to the BEST WESTERN Riverfront Hotel... More

Hotel only $104

5 Radisson Hotel La Crosse

4 stars
4.3 / 5 22 reviews

200 Harborview Plaza Map

Save 25% on your stay

Located in quaint historic downtownon on the beautiful Mississippi River and adjacent to the La Crosse Convention Center. The on site restaurant, Three Rivers Lodge Restaurant, features a 'Taste of Wisconsin' with locally sourced food. Private Plaza Club Level featuring... More

Hotel only $46

6 Super 8 La Crosse

2 stars
3.4 / 5 34 reviews

1625 Rose Street Map

Stay 2, Save 15%

The Super 8 La Crosse, Wisconsin is conveniently located off I-90 at Exit 3/Hwy 53 South. The motel is located near Eau Claire, Wisconsin Dells and Madison, Wisconsin. The Super 8 La Crosse, Wisconsin is just minutes away from the AMTRAK Station. The Super 8 La... More

Hotel only $119

7 Courtyard by Marriott La Crosse Downtown/Mississippi Riverfront

3 stars
4.1 / 5 13 reviews

500 Front Street S Map

Rate includes breakfast

Located on the Banks of the Mississippi River in the heart of historic Downtown, the Courtyard by Marriott La Crosse Hotel features a completely new, renovated environment for your enjoyment and relaxation. We also completed our Lobby reinvention and new Bistro for... More

Hotel only $54

8 Econo Lodge La Crosse

2 stars
2.4 / 5 8 reviews

1906 Rose Street Map

The Econo Lodge of La Crosse, Wisconsin is located at Exit 3 (Hwy 53) off I-90. We are just one mile south of the interstate and only 3 miles from downtown La Crosse, with its many fine restaurants, shops and attractions. The hotel has spacious comfortable & quiet... More

Hotel only $95

9 Candlewood Suites LA CROSSE

2 stars
4.0 / 5 1 reviews

56 Copeland Avenue Map

Walk Downtown from this Hotel's La Crosse Location If you're looking for extended stay hotels in La Crosse, choose the Candlewood Suites® La Crosse, WI hotel and you may be able to forget a rental car. Located within walking distance of popular businesses and restaurants... More

Hotel only $55

10 Quality Inn La Crosse

2 stars
Not yet reviewed

1830 Rose Street Map

The Quality Inn hotel in La Crosse, WI is located near the banks of the Mississippi River. The Quality Inn is three miles from La Crosse Municipal Airport and close to fine dining, shopping, indoor and outdoor activities, and nightlife entertainment. Guests are minutes... More