Isle of Palms Vacations

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Hotel stay must be within date range of Leave and Return.

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Your Isle of Palms vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Isle of Palms vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Isle of Palms travel plans
Build your own Isle of Palms vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Scope out your Isle of Palms vacation options and savings
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Isle of Palms Hotels

From $221

1 Wild Dunes - Destination Hotels and Resorts

4 stars
4.2 / 5 241 reviews

1 Sundial Circle Map

25% OFF, Same Day Sale

The Wild Dunes Resort occupies 1,600 acres of private oceanfront property. The resort encompasses two hotels with two golf courses and 17 Har-Tru tennis courts. Meeting and banquet facilities accommodate up to 300 people and guests have free use of the resort's business... More

From $149

2 The Mills House Wyndham Grand Hotel

4 stars
4.0 / 5 76 reviews

115 Meeting Street Map

Summer Sale - Save 25% on your stay

The Mills House Wyndham Grand Hotel combines opulent accommodations, historic ambiance and modern conveniences in the heart of the city's historic district. It is the only hotel on the city's Museum Mile. Boasting Victorian decor, it was originally built as a hotel in... More

From $111

3 Charleston Harbor Resort and Marina

4 stars
4.0 / 5 290 reviews

20 Patriots Point Road Map

Advance Purchase - Save 15%

There's plenty to do at the Charleston Harbor Resort and Marina even if guests never leave the hotel. Activities include sailing and fishing lessons, a program for kids, evening entertainment on the beach (in season) and the largest marina in the state. The Charleston... More

From $127

4 Seaside Inn

3 stars
3.2 / 5 120 reviews

1004 Ocean Blvd. Map

Save 15%

The newly-renovated Seaside Inn is located in Isle of Palms, named one of the Top 10 Best Beaches in the South by the 2009 Southern Living Readers Choice Awards. The hotel is on the Atlantic Ocean beach. Some of the 51 rooms at the Seaside Inn have ocean views.... More

From $172

5 The Vendue

4 stars
4.3 / 5 123 reviews

19 & 26 Vendue Range Map

Save 10% on 2 Nights

The Vendue Inn offers a prime location in historic French Quarter and upscale services and amenities. This hotel is a combination of two boutique hotels ? 19 Vendue and 26 Vendue. Located just a block from Charleston Waterfront Park, the hotel features a complimentary use... More

From $145

6 The Palms Oceanfront Hotel

3 stars
3.3 / 5 49 reviews

1126 Ocean Blvd Map

Located on the Isle of Palms Beach, The Palms offers affordable oceanfront accommodations and quick access to all the Charleston area has to offer. The Isle of Palms Beach was voted one of the 10 best beaches in the South by readers of Southern Living magazine in 2009.... More

From $178

7 Homewood Suites by Hilton Charleston - Mt. Pleasant

3 stars
4.0 / 5 6 reviews

1998 Riviera Drive Map

Free hot breakfast and high speed internet access

Southern Hospitality in Your Charleston Home BaseLocated close to Charleston hot spots and attractions yet nestled in a quiet residential neighborhood, the Homewood Suites by Hilton® Charleston - Mt. Pleasant hotel is a great home base for touring historic Charleston or... More

From $114

8 Wyndham Garden Charleston Mount Pleasant

3 stars
4.7 / 5 6 reviews

1330 Stuart Engals Blvd Map

Save 20% on your stay

With an exceptional location minutes from glorious beaches, legendary shopping and dining, and the ever-elegant historic downtown Charleston, the Wyndham Garden Charleston Mount Pleasant hotel is South Carolinas oldest and most gracious citys newest upscale hotel. From... More

From $117

9 Holiday Inn Express & Suites MT PLEASANT-CHARLESTON

3 stars
4.4 / 5 76 reviews

350 Johnnie Dodds Blvd. Map

The Holiday Inn Express Hotel & Suites Mt. Pleasant - Charleston is an ecologically-friendly hotel with all the amenities business and leisure travelers expect. All rooms are smoke-free and the hotel actively reduces its use of natural resources. Guests enjoy a free... More

From $212

10 Residence Inn by Marriott Charleston Mt. Pleasant

3 stars
5.0 / 5 5 reviews

1116 Isle of Palms Connector Map

Experience the splendor of the Islands at Residence Inn Charleston-Mt Pleasant. The feel of the West Indies will surround you with comfort and style! Visit the beaches on the Isle of Palms and Sullivans Island, only moments from the hotel. Take in world class golf and... More

  • Promo Code Terms and Conditions

    50TRIP
    Book a qualifying 4+ night flight + hotel vacation package between July 24, 2015 12:00AM CT and September 30, 2015 11:59PM CT, for $1000 or more for travel between July 24, 2015 and December 31, 2015 via Orbitz and instantly receive $50 off the hotel portion of your booking through the use of the promotion code. Limit one discount per hotel room and one promotion code per booking. Discounts are not redeemable for cash for any reason. Promotion codes cannot be resold. Any attempt at fraud will be prosecuted to the fullest extent of the law. Void where prohibited, taxed or restricted. Orbitz reserves the right to change or limit the promotion in its sole discretion. Promo code not valid for Las Vegas, NV bookings.

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