Your Greenville vacation
From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Greenville vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.
Create your own Greenville travel plans
Build your own Greenville vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.
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Reach out to an Orbitz travel specialist for Greenville vacation assistance. Our specialists are available around the clock at 1-800-504-3248. We can even help with last-minute Greenville vacations.
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Scope out your Greenville vacation options and savings
With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.
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Greenville Vacation Packages
Urban retreat located in downtown GreenvilleThe Hyatt Regency Greenville is a stylish urban retreat in the heart of downtown Greenville. With an eight-story atrium lobby, complete with a waterfall, the sense of retreat and relaxation starts as soon as guests walk through... More
120 South Main Street Map
Save 30% on your stay
Four-Diamond hotel in downtown GreenvilleThe elegant art deco-style Westin Poinsett Greenville is an oasis in the heart of downtown Greenville, providing amenities and services for those travelling for both business and pleasure. Charming Main Street shops and a vibrant... More
The Sleep Inn at TD Convention Center is within walking distance to the TD Convention Center and just two miles from Bon Secours Wellness Arena, Bob Jones University, Peace Center and Greenville Technical College. Paris Mountain State Park, Falls Park on the Reedy, Fluor... More
Greenville Hotel's Keeping Southern Charm In Business Greenville is home to some of the Upstate's largest and most exciting industries, including Fluor, Windstream, GE, Michelin and BMW. This Greenville, SC hotel's location is close to the hustle and bustle of Main Street... More
Downtown location, Just minutes away from the Historic Downtown of Greenville, SC. Greenville Memorial Hospital is only mile away. Walking distance to shops and uptown. Free Wi-Fi and Wired internet in all rooms. All of our guest rooms are smoke-free and offer... More
The Comfort Inn & Suites hotel is located in a prime area of Greenville, minutes from Bob Jones University, Furman University, Palmetto Expo Center. We offer many amenities and features, including a free deluxe continental breakfast with hot and cold items as well as a... More
The Extras Aren't Extra at Drury Hotels. Your great rate includes FREE hot food and cold beverages at our 5:30 Kickback. FREE hot breakfast, FREE wireless Internet access and FREE long distance. Our 5:30 Kickback includes a rotating menu of hot and cold items, beer, wine,... More
Whether traveling for business or fun,Courtyard by Marriott® Greenville Downtown makes all of your travels successful by providing exactly what you need: spacious,thoughtful guest rooms;the new Courtyard Bistro and services that help you be more productive and... More
Value lodging offers proximity to business and recreationLa Quinta Inn and Suites Greenville Haywood offers travelers an affordable, comfortable room and a lot of added value in a location convenient to Greenville businesses and shopping. Located off Interstate 385, La... More
Enjoy sunny southern hospitality at this Baymont Inn and Suites Greenville hotel, close to Interstates 85 and 385 and convenient to Furman University and Bob Jones University. This hotel is also convenient to downtown, the ICAR corporate business park, Greenville... More
*Savings based on Flight + Hotel vacation package bookings of 5 or more nights with individual calculable components on www.orbitz.com from January 1, 2014 through June 30, 2014, as compared to price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates, and selected travel supplier(s). Savings not available on all packages.