Picayune Vacations

Hotel options

Hotel stay must be within date range of Leave and Return.

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Your Picayune vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Picayune vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Picayune travel plans
Build your own Picayune vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Scope out your Picayune vacation options and savings
With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.

Picayune Vacation Packages

Hotel only $51

1 Motel 6 New Orleans - Slidell

1 star
2.6 / 5 22 reviews

136 Taos St Map

Motel 6 New Orleans - Slidell is located off I-10 about 2 miles outside of Slidell. Nearby you will find shopping, dining, and museums. All guest rooms have a modern look. Wi-Fi available for a nominal fee and our outdoor pool is open May - October. More

Hotel only $72

2 Holiday Inn Express & Suites PICAYUNE-STENNIS SPACE CNTR.

3 stars
4.6 / 5 9 reviews

1001 Dauphin Street Map

We're the Best Among Picayune, Mississippi Hotels Ideally located along I-59 at exit 4, the Holiday Inn Express Hotel & Suites Picayune is a great home base for area travelers since it's close to Slidell and a short drive from New Orleans, Hattiesburg, and the gulf coast.... More

Hotel only $64

3 La Quinta Inn New Orleans Slidell

3 stars
3.4 / 5 64 reviews

794 East I-10 Service Rd Map

The La Quinta Inn New Orleans-Slidell was recently named a 2013 TripAdvisor Certificate of Excellence award winner! NEW! Samsung Flat-panel TVs with 30 channels of HD programming. Easy-access Plug-and-Play feature makes it simple to connect electronics. Located on the... More

Hotel only $59

4 Econo Lodge Picayune

2 stars
2.7 / 5 3 reviews

550 South Lofton Dr. Map

Our hotel offers a complimentary breakfast along with free high speed internet access. All guest rooms include a microwave and a refrigerator, and we also offer an outdoor pool. Enjoy our managers reception every Wednesday with complimentary food and drinks. We are... More

Hotel only $59

5 Days Inn - Picayune

2 stars
1.0 / 5 3 reviews

450 S Lofton Ave Map

Stay 3, Save 20%

Beautifully appointed hotel within one hour of Biloxi casinos and New Orleans. All rooms have microwaves and refrigerators, iron, iron board, coffee maker, hair dryer, clock, free high speed internet, 32 inch flat screen LED color TV. Complimentary Hot Breakfast with hot... More

Hotel only $42

6 Super 8 Picayune

2 stars
2.3 / 5 3 reviews

999 Cooper Rd Map

Stay 2, Save 15%

Welcome to the Super 8 Picayune, located near Crosby Arboretum, Picayune Street Fair and NASAs John C. Stennis Space Center. Guest will enjoy amenities like a Free Continental breakfast every morning throughout the stay, guest laundromat and complimentary outdoor parking.... More

Hotel only $67

7 Microtel Inn & Suites by Wyndham Pearl River/Slidell

2 stars
4.2 / 5 33 reviews

63537 Hwy 1090 Map

Stay 3, Save 20%

Relax at the consistently enjoyable Microtel Inn and Suites by Wyndham Pearl River/Slidell hotel centrally located on the Gulf Coast at the junction of Interstates 10, 12 and 59 near alligator sightings with Honey Island Swamp Tours, outdoor recreation at Heritage Park,... More

Hotel only $79

8 Hollywood Casino - Hollywood Hotel

2 stars
4.4 / 5 11 reviews

711 Hollywood Blvd Map

Hollywood casino s 14-story hotel is situated on an arnold palmer-designed golf course overlooking the bay of st. louis. The hotel features 291 well-appointed guest rooms and suites. Enjoy las vegas style gaming in our 1200 slot machine casino also offering a variety of... More

Hotel only $109

9 Wingate by Wyndham Slidell/New Orleans East Area

3 stars
4.2 / 5 5 reviews

1752 Gause Blvd E Map

Stay 2, Save 15%

Minutes from New Orleans and the Gulf Coast. Spacious luxurious rooms without the higher prices. You will enjoy free parking with the convenience of being walking distance to restaurants, shopping and Oschner Clinic located right next door. Relax at the bar while... More

Hotel only $56

10 Diamondhead Inn & Suites

3 stars
1.6 / 5 17 reviews

103 Live Oak Dr Map

Stay 4 Nights or More, Save 10%

Conveniently located off I-10 at Exit 16, featuring a huge indoor tropical atrium with swimming pool and large jacuzzi. Suites & guest rooms have free WiFi, cable with 3 Showtime channels & In room coffee. ON SITE: Fire Pit BBQ restaurant, Red Zone Grill &... More

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