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Des Moines Vacations

Your trip

Hotel options

Hotel stay must be within date range of Leave and Return.

Room 1
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Your Des Moines vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Des Moines vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Des Moines travel plans
Build your own Des Moines vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Des Moines Vacation Packages

Hotel only $99

1 Hotel Fort Des Moines

3 stars
3.3 / 5 106 reviews

1000 Walnut St Map

Historic downtown Des Moines hotel with modern amenities, InternetThe historic Hotel Fort Des Moines was built in 1919, and after an extensive renovation was listed on the National Register of Historic Places in 1982. Over the years, the hotel has hosted celebrities such... More

Hotel only $142

2 Hyatt Place Des Moines Downtown

4 stars
4.3 / 5 19 reviews

418 6th Ave. Map

Save 15% on your stay

Guest rooms feature contemporary decor with stylish furnishings including the Hyatt Grand beds, state-of-the-art media and work center with a high-definition 42 inch flat panel television that easily integrates with laptops, a comfortable cozy corner L-shaped... More

Hotel only $95


3 stars
3.8 / 5 26 reviews

1050 6th Avenue Map

Downtown Des Moines hotel with free wireless, parking, airport shuttleThe Holiday Inn Des Moines Downtown Mercy Campus is located close to Mercy Medical Center and Wells Fargo Arena and Iowa Events Center. Welcome amenities include free parking, an airport shuttle service... More

Hotel only $127

4 Embassy Suites Hotel Des Moines Downtown

3 stars
3.9 / 5 44 reviews

101 East Locust Street Map

Free cooked-to-order breakfast, Evening Reception

Downtown Des Moines hotel offers all-suites accommodations on RiverwalkThe Embassy Suites Des Moines - On the River offers all-suite accommodations in downtown Des Moines near the capitol, the East Village and Court Avenue District. The hotel is on the Principal... More

Hotel only $114

5 Quality Inn & Suites Event Center

2 stars
3.2 / 5 5 reviews

929 3rd Street Map

The Quality Inn & SuitesTM Event Center is centrally located near many popular attractions, including the Iowa Events Center, Des Moines Botanical Center, Hoyt Sherman Place, Drake University and the Science Center of Iowa. The Des Moines International Airport is located... More

Hotel only $129

6 Renaissance Des Moines Savery Hotel

4 stars
4.2 / 5 25 reviews

401 Locust Street Map

Rate includes breakfast

Elegant, historic skywalk hotel welcomes famous and non-famous alikeThe elegant Renaissance Des Moines Savery Hotel has hosted presidents and is listed on the National Register of Historic Places. A classy lobby with a chandelier welcomes famous and non-famous guests. Its... More

Hotel only $129

7 Des Moines Marriott Downtown

3 stars
4.0 / 5 30 reviews

700 Grand Avenue Map

Rate includes breakfast

Large downtown Des Moines hotel with business and leisure amenitiesThe 33-floor Des Moines Marriott Downtown offers 411 guest rooms, six luxury suites and 15 meeting rooms. The skywalk system connects the hotel with other downtown businesses. High-end amenities include an... More

Hotel only $119

8 Residence Inn Des Moines Downtown

3 stars
3.5 / 5 2 reviews

100 SW Water Street Map

The NEW Residence Inn by Marriott, the only all- suite, extended stay hotel in downtown Des Moines sits on the scenic river, close to Principal Park, Court Avenue Entertainment District, Science Center of Iowa and the Iowa Events Center. We have spacious studio,... More

Hotel only $50

9 Travelodge Des Moines IA

3 stars
2.8 / 5 65 reviews

4685 A Northeast 14th Street Map

Stay 2, Save 15%

Des Moines hotel with free breakfast, wireless Internet, outdoor poolThe Travelodge Des Moines IA sits north of the city just off I-35/I-80 and I-235. The Des Moines hotel offers a free breakfast, free wireless Internet and free local calls. Children under 12 stay free... More

Hotel only $89

10 Econo Lodge Inn & Suites Fairgrounds

2 stars
3.0 / 5 5 reviews

410 E. 30th Street Map

Hotel has a 100% smoke free environment. Experience the Econo Lodge Inn and Suites, Des Moines newest hotel located adjacent to the Iowa State Fairgrounds and only minutes from downtown Des Moines and the Iowa Event and Hy-Vee Center. All rooms have coffee makers, hair... More