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Panama City Vacations

Your Panama City vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Panama City vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Panama City travel plans
Build your own Panama City vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

Find Panama City travel discounts
Be the first to know about exclusive offers and last-minute deals on Panama City travel. Sign for our deals e-mail , or follow us on Twitter and Facebook for promo codes, discounts and more. Our global network of travel experts find big-time savings and travel deals just for you.

Get Panama City travel support 24/7
Reach out to an Orbitz travel specialist for Panama City vacation assistance. Our specialists are available around the clock at 1-800-504-3248. We can even help with last-minute Panama City vacations.

Sign up for free Panama City travel alerts
Make travel plans smoother with Orbitz Care Alerts. Receive real-time info about flight delays, weather and other events via phone, e-mail or text. Keep up to six other people in the loop with travel alerts, too.

Scope out your Panama City vacation options and savings
With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.

Panama City Vacation Packages

Hotel only $51

1 Motel 6 Destin FL

1 star
2.9 / 5 95 reviews


Budget-friendly motel near the action in DestinThe Motel 6 Destin FL makes a great base-camp for Emerald Coast activities. The clean, well-kept hotel sits on Destin Harbor and is located within minutes of white-sand beaches and many other attractions. It has a refreshing... More

Hotel only $97

2 Sandestin Golf and Beach Resort

4 stars
3.6 / 5 168 reviews



Destin mega-resort offering beach, bay and fairwaysWith miles of beach- and bay-front, dozens of neighborhoods dotted with stocked lakes and its own village with eateries, shops and clubs, the 2,400-acre Sandestin Golf and Beach Resort is more like a mini city than an... More

Hotel only $80

Panama City hotel offers family fun on the beachThe Holiday Inn Resort Panama City Beach features tropical foliage encircling the enormous pool, where guests can spend the day reclined in lounge chairs, splashing in the waterfall, or taking the private walkway onto Panama... More

4 Origin at Seahaven

3 stars
3.8 / 5 292 reviews


Spacious condominiums near beach offer comforts of homeThe spacious condominiums at the Origin at Seahaven are luxuriously furnished with solid wood headboards and furniture, custom light fixtures and granite countertops. Its grand tiled pool terrace overlooks the Gulf... More

Hotel only $67

Origin Beach Resort is an affordable luxury condominium just 150 feet from the sugar white sands of the Gulf of Mexico. Origin, created and designed with the guidance from world renowned Playground Development, is the only interior corridor entrance resort on Panama City... More

6 Seahaven Beach Hotel

2 stars
3.0 / 5 124 reviews


Panama City Beach hotel offers private balconies in every roomWake up every morning to the gentle waves of the Gulf lapping up on the white sands right outside every room at the Seahaven Beach Hotel. The heated swimming here, with a large, partially covered patio area,... More

Hotel only $57

7 Beachbreak by the Sea Resorts

3 stars
2.9 / 5 78 reviews


While the Beachbreak by the Sea may be small- it stands only four stories in a sea of high-rises- the resort is big on warmth and charm. One of By the Sea Resorts three gulf-front Panama City Beach hotels, the Beachbreak offers 97 newly-renovated rooms and an array of... More

Hotel only $92

8 Sterling Resorts- Laketown Wharf

3 stars
4.1 / 5 38 reviews


Save 50% Off

Laketown Wharf is known for its signature water feature, a massive lighted fountain within its namesake lake, choreographed with dancing water, lights and music into a nightly landmark show. Families enjoying their vacations at Laketown Wharf can experience the ultimate... More

Hotel only $69

Family-friendly hotel near downtown and beachesThe La Quinta Inn & Suites Panama City offers ideal access to both the buzz of downtown Panama City and the sugar-sand stretches of Panama City Beach. Its lush courtyard, large outdoor pool and whirlpool offer an on-site... More

Hotel only $59

10 Days Inn Panama City Beach/Ocean Front

2 stars
3.4 / 5 186 reviews


Stay 3, Save 20%

Panama City hotel offers comfort and convenienceAll guest rooms have private balconies that face the beach and the emerald Gulf waters at the Days Inn Panama City/Ocean Front. Guests can stroll those sugar-like sands endlessly or play in the six-story-high waterfall that... More