Panama City Vacations
From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Panama City vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together. Panama City
Create your own Panama City travel plans
Build your own Panama City vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.
Find Panama City travel discounts
Be the first to know about exclusive offers and last-minute deals on Panama City travel. Sign for our deals e-mail , or follow us on Twitter and Facebook for promo codes, discounts and more. Our global network of travel experts find big-time savings and travel deals just for you.
Get Panama City travel support 24/7
Reach out to an Orbitz travel specialist for Panama City vacation assistance. Our specialists are available around the clock at 1-800-504-3248. We can even help with last-minute Panama City vacations.
Sign up for free Panama City travel alerts
Make travel plans smoother with Orbitz Care Alerts. Receive real-time info about flight delays, weather and other events via phone, e-mail or text. Keep up to six other people in the loop with travel alerts, too.
Scope out your Panama City vacation options and savings
With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.
Panama City Hotels
|Detroit||Panama City||Fri, Jun 14 - Mon, Jun 24||$453|
|Chicago||Panama City||Fri, Jun 14 - Fri, Jun 21||$446|
|Milwaukee||Panama City||Wed, Jun 5 - Sun, Jun 9||$446|
|Boston||Panama City||Tue, Jun 18 - Sun, Jun 23||$443|
|Minneapolis||Panama City||Sun, Jun 23 - Sun, Jun 30||$508|
|Denver||Panama City||Mon, Jun 10 - Mon, Jun 17||$436|
|Baltimore||Panama City||Tue, Jun 4 - Tue, Jun 18||$270|
|New York||Panama City||Wed, Jun 12 - Wed, Jun 19||$386|
|Washington DC||Panama City||Fri, Jun 7 - Wed, Jun 19||$433|
|St Louis||Panama City||Thu, Jun 6 - Tue, Jun 11||$294|
|Buffalo||Panama City||Fri, Jun 21 - Tue, Jul 2||$366|
|Indianapolis||Panama City||Fri, Jun 21 - Fri, Jun 28||$364|