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Key Largo Vacations

Your trip

Hotel options

Hotel stay must be within date range of Leave and Return.

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Your Key Largo vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Key Largo vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

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Build your own Key Largo vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Key Largo Vacation Packages

Hotel only $124

1 Bayside Inn Key Largo

3 stars
3.0 / 5 66 reviews

99490 Overseas Highway Map

Weekday Sale 15% Off

Revitalize at the waterfront heated pool, swimming lagoon, fish from our pier or simply relax under swaying palms in a tropical breeze as this Key Largo hotels delivers. You may wish to stay in your room and enjoy room service from Sushi Nami. We are located near John... More

Hotel only $130

2 Marina Del Mar Resort & Marina Key Largo

2 stars
3.4 / 5 146 reviews

527 Caribbean Drive Map

Oceanside Key Largo hotel with marina and apartment-style accomodationsLocated on Key Largo Harbor, the Marina Del Mar Resort and Marina Key Largo offers apartment-style accommodations within close proximity to local diving and fishing charters, restaurants, and John... More

Hotel only $194

3 Hampton Inn Key Largo, FL

3 stars
4.3 / 5 57 reviews

102400 Overseas Highway PO Box 1024 Map

Free On The House hot breakfast, Wi-Fi

dive in for an adventure...welcome to the Hampton Inn Key Largo The Hampton Inn® Key Largo may be located just a one hour drive from Miami, but when you're deep underneath the sparkling blue waters off the coast of Florida's northernmost key island, we bet you'll feel a... More

Hotel only $109

4 Rodeway Inn & Suites Key Largo

2 stars
3.1 / 5 30 reviews

99202 Overseas Highway Map

The hotel is centrally located in Key Largo near popular attractions and restaurants. Located just three blocks from the ocean, this Rodeway Inn and Suites is a great place to stay after a fun day at the beach. Onsite is a PADI five star-certified scuba diving shop and a... More

Hotel only $208

5 Holiday Inn KEY LARGO

3 stars
3.9 / 5 104 reviews

99701 Overseas Hwy Map

Affordable motel rooms, ideal watersports location on Key Largo Harbor The Holiday Inn Key Largo Resort offers a location and amenities ideal for families and individuals looking to absorb themselves in everything Key Largo has to offer. Located only 55 minutes from... More

Hotel only $249

6 Courtyard Key Largo

2 stars
3.8 / 5 26 reviews

99751 Overseas Highway Map

Rate includes breakfast

Travel to Key Largo and discover why the Florida Keys are so very special. The Courtyard by Marriott Key Largo offers 91 newly renovated rooms and deluxe suites, each with a private balcony and dramatic view. Our marina waterfront location offers easy access to everything... More

Hotel only $179

7 Hilton Key Largo Resort

3 stars
3.6 / 5 102 reviews

97000 Overseas Highway Map

Includes two breakfast buffet certificates

Secluded hotel with luxury rooms, amenities on private Key Largo beachBordered by picturesque Florida Bay and the Gulf of Mexico, Hilton Key Largo sits nestled among 13 acres of lush hardwood forest along the Gulf of Mexico and the southern boundary of Everglades National... More

Hotel only $269

8 Key Largo Bay Marriott Beach Resort

4 stars
4.0 / 5 92 reviews

103800 Overseas Highway, MM 103.8 Map

Rate includes breakfast

Key Largo luxury hotel with private beach, on-site watersports center The Key Largo Bay Marriott Beach Resort sits on 17 lush acres of waterfront paradise about an hour south of Miami. Located at the heart of Key Largo, a scuba diving and fishing Mecca, the Key Largo Bay... More

9 Mariner's Resort Villas and Marina by Keys Caribbean

4 stars
3.8 / 5 55 reviews

97501 Overseas Hwy. Map

Family-friendly condos with kitchens, laundries and on-site activities A secluded hideaway, Mariner's Resort Villas and Marina offers condo-style accommodations toward the south end of Key Largo with on-site activities and access to watersports. Guests should take... More

Hotel only $179

10 Dove Creek Lodge, an Ascend Hotel Collection Member

3 stars
4.5 / 5 23 reviews

147 Seaside Avenue, MM 94.5 Oceanside Map

Hidden Key Largo gem with views of the Atlantic OceanLocated in the Florida Keys on the ocean side of Key Largo is Dove Creek Lodge, a boutique style hotel that is perfect for a romantic getaway or unique business retreat. Stories about Ernest Hemmingway's Caribbean... More