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Santa Ana Vacations

Your trip

Hotel options

Hotel stay must be within date range of Leave and Return.

Room 1
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Your Santa Ana vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Santa Ana vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Santa Ana travel plans
Build your own Santa Ana vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Santa Ana Vacation Packages

Hotel only $63

1 Comfort Inn & Suites John Wayne Airport

2 stars
3.0 / 5 93 reviews

2620 Hotel Terrace Dr. Map

Save 15% on your stay

Comfort Inn and Suites John Wayne Airport hotel, located two miles from Orange County John Wayne Airport, offers free airport shuttle, free hot breakfast buffet, free WIFI, heated pool and hot tub. Enjoy our quiet tropical surroundings in a relaxing courtyard. All guest... More

Hotel only $89

2 Embassy Suites Santa Ana - Orange County Airport North

3 stars
3.9 / 5 31 reviews

1325 East Dyer Road Map

Free cooked-to-order breakfast, Evening Reception

A gem among Santa Ana hotels, Embassy Suites Santa Ana - Orange County Airport North hotel features comfortable accommodations and a full range of thoughtful amenities. Set just two-and-a-half miles from John Wayne/Orange County Airport, this all-suite hotel is located... More

Hotel only $75

3 La Quinta Inn & Suites Orange County - Santa Ana

3 stars
3.7 / 5 198 reviews

2721 Hotel Terrace Map

Orange County hotel close to great Southern California attractionsClose to beaches, shopping, family fun and business facilities, La Quinta Inn & Suites Orange County Santa Ana is a budget-friendly choice for visitors looking for a work, fun or both. La Quinta Inn... More

Hotel only $79

4 Courtyard Santa Ana Orange County

3 stars
4.1 / 5 20 reviews

8 MacArthur Place Map

Rate includes breakfast

If youre looking for hotels in Santa Ana, CA, you'll find our stylish Courtyard Santa Ana Orange County hotel is perfect for business or pleasure. Our Santa Ana hotel is near John Wayne Airport and Orange County attractions like South Coast Plaza, Anaheim Convention... More

Hotel only $89

5 Quality Suites John Wayne Airport

3 stars
4.0 / 5 90 reviews

2701 Hotel Terrace Dr. Map

Comfortable, smoke-free hotel near Orange County airport and businesses Quality Suites John Wayne Airport is a haven for busy Orange County business person. Business travelers enjoy conveniences like free high-speed Wireless Internet access in all rooms, free local calls,... More

Hotel only $89

6 Doubletree Club Orange County Airport/Santa Ana

4 stars
3.8 / 5 39 reviews

7 Hutton Centre Drive Map

Rate includes Breakfast, Internet, Parking

The Doubletree Club hotel by the Orange County Airport is located lakeside in the heart of Orange County's South Coast Metro Business Center, a mile from Orange County-John Wayne Airport (SNA). Our well-located hotel is a half mile from Irvine and Costa Mesa business... More

Hotel only $95

7 BEST WESTERN PLUS Orange County Airport North

3 stars
3.7 / 5 83 reviews

2700 Hotel Ter Map

Located in central Orange County, near the Orange County Airport, this Santa Ana hotel offers something for everyone, plus a great location and rates. Stay at this Santa Ana hotel to enjoy the best Orange County has to offer. Families will love visiting nearby... More

Hotel only $89

8 Doubletree Hotel Santa Ana/Orange County Airport

3 stars
3.9 / 5 42 reviews

201 East MacArthur Boulevard Map

Internet and Parking 58% Off

The Doubletree Hotel Santa Ana by the Orange County Airport is located in the heart of Orange County business districts for the cities of Irvine, Tustin, and Costa Mesa. With easy access to the 405, 55 and 5 Freeways, our full service hotel is minutes from John Wayne /... More

Hotel only $114

9 Courtyard by Marriott Costa Mesa South Coast Metro

3 stars
3.7 / 5 18 reviews

3002 Map

Rate includes breakfast

Our centrally located Courtyard Santa Ana Hotel near Costa Mesa, California offers the perfect place to stage your Orange County adventure. Enjoy a prime location 9 miles north of popular Anaheim attractions including Disneyland and Angel Stadium. 15 minutes down the 405... More

Hotel only $86


3 stars
4.0 / 5 22 reviews

2726 South Grand Avenue Map

Centrally located in the heart of Orange County, the Holiday Inn Orange County Airport Hotel Santa Ana is the perfect location for both business and leisure travelers offering 176 newly renovated, well appointed guest rooms and recently recipient of the 2013 IHG Hotel... More