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La Mesa Vacations

Your La Mesa vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for La Mesa vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own La Mesa travel plans
Build your own La Mesa vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Reach out to an Orbitz travel specialist for La Mesa vacation assistance. Our specialists are available around the clock at 1-800-504-3248. We can even help with last-minute La Mesa vacations.

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With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.

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La Mesa Vacation Packages

Hotel only $84

1 Holiday Inn SAN DIEGO - LA MESA

3 stars
3.8 / 5 47 reviews

8000 Parkway Drive Map

Welcome to Holiday Inn San Diego - La Mesa ! San Diego flows with the charisma of its Spanish settlers, with sun, sand, beaches, mountains, world class golf courses and lakes providing a wide array of options to both business and leisure travelers. This Holiday Inn is... More

Hotel only $44

2 Heritage Inn La Mesa

2 stars
2.2 / 5 56 reviews

7851 Fletcher Parkway Map

Winter Promo Save 10%

The Heritage In La Mesa is centrally located in the heart of San Diego East county off the I-8 just two miles east of San Diego State University. The hotel is within minutes to all major San Diego attractions. The 105 room hotel offers clean comfortable rooms at an... More

Hotel only $80

3 Holiday Inn Express SAN DIEGO-LA MESA (SDSU AREA)

3 stars
3.8 / 5 52 reviews

9550 Murray Drive Map

La Mesa Hotel's Decor Shows Latin Influence Whether coming to "America's Finest City" for beaches or business, the savvy traveler is sure to find "The Jewel of the Hills" in La Mesa. The hotel's convenient location puts you minutes from some of San Diego's biggest... More

Hotel only $55

4 Rodeway Inn La Mesa

1 star
2.7 / 5 19 reviews

4210 Spring Street Map

The Rodeway Inn hotel at La Mesa is conveniently located on Spring Street, just one mile from Interstate 8 and close to San Diego and its many attractions. This La Mesa hotel is minutes from popular attractions, including Qualcomm Stadium, Balboa Park, Mission Bay Park,... More

Hotel only $63

5 Days Inn & Suites San Diego SDSU

2 stars
2.8 / 5 20 reviews

7475 El Cajon Blvd Map

Stay 2, Save 15%

Welcome to the Days Inn and Suites San Diego, CA. This all Suite non-smoking property offers suites with a living room and a separate bedroom. We are conveniently located close to I-8 just 1 mile from San Diego State UniversitySDSU. You will find yourself centrally... More

Hotel only $59

6 Super 8 San Diego Area/La Mesa

1 star
3.4 / 5 12 reviews

6952 University Avenue Map

Stay 2, Save 15%

Beautifully Renovated Rooms. Free Wireless High Speed Internet Access. Free Continental Breakfast. Easy Access to Local Freeways. Fast Food Dining Within Walking Distance Please be advised that guests must be 21 years or older with a valid government I.D. to check-in.... More

Hotel only $51

7 Motel 6 San Diego - La Mesa

1 star
2.6 / 5 5 reviews

7621 Alvarado Rd Map

Motel 6 San Diego - La Mesa is located within walking distance to area restaurants. Ride the San Diego Trolley and shop in Old Town San Diego, 10 miles. Californias Marina Park Beach is just 10 miles. Wi-Fi is available in all guest rooms for a fee. More