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Florence Vacations

Your trip

Hotel options

Hotel stay must be within date range of Leave and Return.

Room 1
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Your Florence vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Florence vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Florence travel plans
Build your own Florence vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

Find Florence travel discounts
Be the first to know about exclusive offers and last-minute deals on Florence travel. Sign for our deals e-mail , or follow us on Twitter and Facebook for promo codes, discounts and more. Our global network of travel experts find big-time savings and travel deals just for you.

Get Florence travel support 24/7
Reach out to an Orbitz travel specialist for Florence vacation assistance. Our specialists are available around the clock at 1-800-504-3248. We can even help with last-minute Florence vacations.

Sign up for free Florence travel alerts
Make travel plans smoother with Orbitz Care Alerts. Receive real-time info about flight delays, weather and other events via phone, e-mail or text. Keep up to six other people in the loop with travel alerts, too.

Scope out your Florence vacation options and savings
With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.
 

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Florence Vacation Packages

Hotel only $75

1 Hampton Inn Florence-Midtown

3 stars
4.1 / 5 9 reviews

2281 Florence Blvd. Map

Free On The HouseT hot breakfast, Wi-Fi

small town southern charm meets big city excitement...welcome to the Hampton Inn Florence-Midtown.Located on the banks of the beautiful Tennessee River, Florence, Alabama, is rich with Native American and Civil War history. This picturesque area in the Northwest corner of... More

Hotel only $99

2 Residence Inn Florence

3 stars
4.8 / 5 4 reviews

1000 Sweetwater Avenue Map

The Residence Inn by Marriott has been awarded by the City of Florence, Alabama as a certified "Green" hotel in the Shoals area. Whether you are traveling to this beautiful river locked city for a sporting event like a UNA football game, tournament fishing, or swinging a... More

Hotel only $75

3 Quality Inn Florence

2 stars
4.3 / 5 3 reviews

150 Etta Gray Drive Map

Walking distance to major shopping and restaurants. Easy access off Hwy 72, 43, and 133. The most restful stay in Shoals Area. Pet accomodation: 10 USD per pet/night. Pet limit: Max 15 lbs, 2 per room.Free Hot Breakfast. More

Hotel only $52

4 Knights Inn Florence

2 stars
2.0 / 5 2 reviews

1915 Florence Blvd Map

Stay 2, Save 15%

Knights Inn Florence, AL ideally located just minutes from historic downtown Florence, is located on 2.5 acres of lush landscaped courtyards with a gazebo and outdoor pool. Approximately 42 miles west of I-65 on Highway 72. Lounge around our beautiful outdoor pool or... More

Hotel only $63

5 Baymont Inn & Suites Florence/Muscle Shoals

2 stars
3.1 / 5 8 reviews

115 Ana Dr Map

Stay 3, Save 20%

Enjoy the sunny southern hospitality at this Baymont Inn and Suites Florence/Muscle Shoals, convenient to the University of North Alabama and great Alabama attractions like the Alabama Music Hall of Fame, the Helen Keller Birthplace and the Natchez Trace Parkway. Pets are... More

Hotel only $88

6 Hampton Inn & Suites Florence-Downtown

2 stars
4.3 / 5 4 reviews

505 South Court Street Map

Free On The HouseT hot breakfast, Wi-Fi

come visit the best kept secret in North Alabama...welcome to the Hampton Inn & Suites Florence/Downtown, AL. From the rushing waters of the Tennessee River to our south to the tranquil beauty of historic Florence to our north the Hampton Inn & Suites® hotel in... More

Hotel only $179

7 Marriott Shoals Hotel & Spa

3 stars
4.0 / 5 6 reviews

10 Hightower Place Map

Rate includes breakfast

Inspired by Southern hospitality, discover a hotel in Florence, Alabama where conservative elegance meets the beauty of nature. The Marriott Shoals Hotel & Spa is set in the Tennessee River Valley, inviting you to experience a new level of refinement and charm amongst... More

Hotel only $94

8 Holiday Inn Express & Suites FLORENCE NORTHEAST

3 stars
3.7 / 5 6 reviews

180 ETTA GRAY STREET Map

Our Florence, Alabama Hotel's Near the Tennessee River The Holiday Inn Express® Florence Northeast Hotel is located in the northwest corner of Alabama, an area best known for its variety of outdoor activities. As you visit this friendly town, pause to enjoy the... More

Hotel only $105

9 Comfort Suites Florence

2 stars
3.8 / 5 4 reviews

140 Matthew Paul Court Map

The Comfort Suites Florence was built in 2010 and is located on the banks of the Tennessee River. Whether you are there for business or pleasure, this hotel has all the comforts of home with great dining and shopping just minutes away. Great fishing and golfing are also... More