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Mayaguez, Cabo Rojo Vacations

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Hotel stay must be within date range of Leave and Return.

Room 1
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Your Mayaguez, Cabo Rojo vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Mayaguez, Cabo Rojo vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Mayaguez, Cabo Rojo travel plans
Build your own Mayaguez, Cabo Rojo vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Mayaguez, Cabo Rojo Vacation Packages

Hotel only $88

1 Howard Johnson Inn Downtown Mayaguez PR

2 stars
3.5 / 5 58 reviews

Calle Mendez Vigo 70 Este Map

Stay 2, Save 15%

Historic landmark in Mayaguez, Puerto Rico Howard Johnson Inn, a converted monastery located next to the main cathedral on Plaza Colon in Mayaguez, Puerto Rico, features tile floors and walkways, superb views from the open walkways, and numerous amenities. Guests at this... More

Hotel only $111

2 Holiday Inn MAYAGUEZ & TROPICAL CASINO

3 stars
3.9 / 5 51 reviews

2701 HIGHWAY #2,HOSTOS AVENUE Map

Affordable lodging on the coast in Mayaguez, Puerto Rico Holiday Inn Mayaguez and El Tropical Casino, conveniently situated in Mayaguez, provides easy access to the best attractions of Porta Del Sol. Leisure travelers head to Mayaguez for its proximity to attractions... More