Panama City Vacations

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Hotel stay must be within date range of Leave and Return.

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Your Panama City vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Panama City vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Panama City travel plans
Build your own Panama City vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

Find Panama City travel discounts
Be the first to know about exclusive offers and last-minute deals on Panama City travel. Sign for our deals e-mail , or follow us on Twitter and Facebook for promo codes, discounts and more. Our global network of travel experts find big-time savings and travel deals just for you.

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Reach out to an Orbitz travel specialist for Panama City vacation assistance. Our specialists are available around the clock at 1-800-504-3248. We can even help with last-minute Panama City vacations.

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Make travel plans smoother with Orbitz Care Alerts. Receive real-time info about flight delays, weather and other events via phone, e-mail or text. Keep up to six other people in the loop with travel alerts, too.

Scope out your Panama City vacation options and savings
With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.

Panama City Vacation Packages

Hotel only $112

1 Hard Rock Hotel Panama Megapolis

5 stars
4.4 / 5 76 reviews

Avenida Balboa Multicentro Map

Book Now and Save 40%

Rock-and-roll-themed hotel near the Panama CanalThe Hard Rock Hotel Panama Megapolis is a new hotel located right in the center of the city, close to the shops, history and local culture. All sixty-six stories of the 3-star hotel tower block are dedicated to the... More

Hotel only $79

2 Veneto a Wyndham Grand Hotel and Casino

4 stars
3.7 / 5 140 reviews

Avenido Eusebio A. Morales y Via Veneto Map

FREE Wireless Internet & Parking

City centre hotel ideal for business and leisureVeneto Wyndham Grand Hotel and Casino is a comfortable urban hotel that offers well-maintained rooms and suites as well as recreation and business facilities in the heart of the vibrant and heritage-rich Panama City.... More

Hotel only $62

3 Tryp By Wyndham Panama Centro

3 stars
4.2 / 5 27 reviews

Ave 49B Norte (Via Veneto), El Cangrejo Map

FREE Breakfast, Wi-Fi, Parking, Use of Gym & Sauna

Urban spaces in central PanamaTryp By Wyndham Panama Centro invites travelers to the deluxe accommodations and modern amenities strategically set in the heart of Panama. This city center hotel places holidaymakers near Museo de Arte Contemporaneo, Parque Natural... More

Hotel only $62

4 DoubleTree by Hilton Hotel Panama City

3 stars
4.3 / 5 33 reviews

Via. Espana & Federico Boyd Bella V Map

Signature chocolate chip cookie at check-in

Central hotel near Panama Vieja and Casco ViejoOffering comfortably furnished spaces set in the financial district of the city, DoubleTree by Hilton Hotel Panama City makes for a suitable base for corporate and leisure travelers in Panama City. This city centre hotel... More

Hotel only $73

5 Continental Hotel and Casino

3 stars
3.6 / 5 72 reviews

Via Espana and Ricardo Arias Street Map

FREE WiFi and Parking

Panama hotel with 24-hour restaurant, pool and Wurlitzer organ bar Located along the commercial zone of Via Espana, the environmentally-conscious Riande Continental Hotel and Casino boasts a 24-hour restaurant know for live Wurlitzer pipe organ entertainment on Tuesday... More

Hotel only $103

6 Riande Aeropuerto Hotel & Casino

4 stars
3.9 / 5 182 reviews

Via Tocumen Panama Map

Book Now and Save!

Palm-punctuated, Panama City hotel with pool, not far from airport Located one mile from Tocumen International Airport, the family-friendly Riande Aeropuerto Hotel and Resort features an outdoor pool surrounded by palm trees, a health club and inclusive breakfast.... More

Hotel only $169

7 Trump Ocean Club International Hotel and Tower Panama

5 stars
4.5 / 5 51 reviews

Calle Punta Colon Map

Towering hotel with opulent spaces and upscale amenitiesTrump Ocean Club International Hotel and Tower Panama features elegant accommodations and state-of-the-art amenities housed in the tallest building in Central America. This Panama hotel offers social and corporate... More

Hotel only $99

8 Tryp by Wyndham Panama at Albrook Mall

4 stars
4.3 / 5 12 reviews

Centro Comercial Albroook Mall Map

Book Now and Save 10!

The Hotel offers the following amenities: 331 comfortable guest rooms One international restaurant, one lobby bar, rooftop bar and coffee shop Complimentary High Speed WiFi with 30MB of bandwidth 30,299 square feet of meeting space Spectacular rooftop solarium and... More

Hotel only $109

9 RIU Plaza Panama

5 stars
4.4 / 5 87 reviews

Calle 50 con 53 Este Map

Free WiFi plus Free Buffett Breakfast & MORE

Business luxury in central PanamaRiu Plaza Panama welcomes corporate and leisure travelers to contemporary accommodations and deluxe facilities for business functions situated in the heart of the financial district of Panama City. Holidaymakers at this luxury hotel are... More

Hotel only $173

10 Riu Playa Blanca All Inclusive

4 stars
4.0 / 5 9 reviews

Finca 43.688 Provincia de Cocle Map

$35 Spa Credit per person + Golf Discount

Hotel Riu Playa Blanca (All Included 24h) Opening in Spring 2014, Located on the Pacific Coast of Panama on the Beachfront. 24 Hours All Inclusive, with all meals, unlimited drinks and Snacks. Services available are 4 Restaurants and 4 bars. Highlights: *Opening in... More

  • Promo Code Terms and Conditions

    Book a qualifying 4-night flight + hotel vacation package between January 1, 2014 12:00AM CST and June 30, 2015 11:59PM CST, for $1000 or more for travel between January 1, 2014 and September 30, 2015 via Orbitz and instantly receive $150 off the hotel portion of your booking through the use of the promotion code. Limit one discount per hotel room and one promotion code per booking. Discounts are not redeemable for cash for any reason. Promotion codes cannot be resold. Any attempt at fraud will be prosecuted to the fullest extent of the law. Void where prohibited, taxed or restricted. Orbitz reserves the right to change or limit the promotion in its sole discretion. Promo code not valid for Las Vegas, NV bookings.

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