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Panama City Vacations

Your trip

Hotel options

Hotel stay must be within date range of Leave and Return.

Room 1
Age categories
Ages of children at time of trip (for pricing, discounts)

Your Panama City vacation

From family vacations to last-minute romantic getaways, make Orbitz your first and only stop for Panama City vacations. You can customize your trip with flights, hotels and activities to match your travel plans and tastes. Sweeten the pot with extra savings when you book your flight and hotel together.

Create your own Panama City travel plans
Build your own Panama City vacation itinerary. Choose a flight that matches your schedule and a hotel with the amenities you need. Book them together for extra discounts you won't find when booking separately.

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Reach out to an Orbitz travel specialist for Panama City vacation assistance. Our specialists are available around the clock at 1-800-504-3248. We can even help with last-minute Panama City vacations.

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Make travel plans smoother with Orbitz Care Alerts. Receive real-time info about flight delays, weather and other events via phone, e-mail or text. Keep up to six other people in the loop with travel alerts, too.

Scope out your Panama City vacation options and savings
With the Orbitz Matrix Display, you can view all your flight and hotel options quickly. Plus, you'll see what you can save on your travel packages when you book them together.

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Panama City Vacation Packages

Hotel only $70

1 Continental Hotel and Casino

3 stars
3.5 / 5 69 reviews

Via Espana and Ricardo Arias Street Map

FREE WiFi and Parking

Panama hotel with 24-hour restaurant, pool and Wurlitzer organ bar Located along the commercial zone of Via Espana, the environmentally-conscious Riande Continental Hotel and Casino boasts a 24-hour restaurant know for live Wurlitzer pipe organ entertainment on Tuesday... More

Hotel only $95

2 Riande Aeropuerto Hotel & Casino

4 stars
3.6 / 5 178 reviews

Via Tocumen Panama Map

Free Shuttle Round-Trip+FREE WiFi & Parking

Palm-punctuated, Panama City hotel with pool, not far from airport Located one mile from Tocumen International Airport, the family-friendly Riande Aeropuerto Hotel and Resort features an outdoor pool surrounded by palm trees, a health club and inclusive breakfast.... More

Hotel only $78

3 Veneto a Wyndham Grand Hotel and Casino

4 stars
3.9 / 5 168 reviews

Avenido Eusebio A. Morales y Via Veneto Map

FREE Wireless Internet & Parking

This modern adults only hotel is located 200 metres from Via Espana, in Panama Citys main business district. It offers a spa and outdoor pool, and it has its own casino.The elegant, air conditioned rooms at the Veneto A Wyndham Grand Hotel and Veneto Casino feature cable... More

Hotel only $129

4 Riu Plaza Panama

5 stars
4.4 / 5 69 reviews

Calle 50 con 53 Este Map

30%Off per Night + Best Breakfast in town for FREE

Riu Plaza Panama is a captivating hotel located near large shopping centers, entertainment hotspots and the vibrant nightlife of the city. Stay in the newest and one of the most luxurious hotel in Panama City, a project as cosmopolitan as the city itself. Riu Plaza... More

Hotel only $162

5 Trump Ocean Club International Hotel and Tower Panama

5 stars
4.4 / 5 38 reviews

Calle Punta Colon Map

"Commanding the oceanview on the exclusive peninsula of Punta Pacifica, Trump Ocean Club International Hotel & Tower raises 70 stories above Panama Bay, with views extending to the Pearl Islands and the Pacific Ocean beyond" With Trump Ocean Club, The Trump... More

Hotel only $68

6 Tryp By Wyndham Panama Centro

3 stars
4.1 / 5 10 reviews

Ave 49B Norte (Via Veneto), El Cangrejo Map

FREE Breakfast, Wi-Fi, Parking, Use of Gym & Sauna

Tryp Panama Centro is located at the city centre, just at 20 minutes drive from Panama International Airport. Our location puts you walking distance to the new METRO Station and from Panama financial distrit, the best restaurants, shopping and Nightlife. Air-conditioned... More

Hotel only $101

7 Hotel Plaza Paitilla Inn

3 stars
3.0 / 5 8 reviews

Via Italia, Punta Paitilla, Calle Wiston Churchill Map

FREE Parking, Wireless Internet & Buffet Breakfast

Plaza Paitilla Inn Hotel in Panama city, with comfortable rooms, at 15 minutes from the international airport and 5 minutes from the banking area, offer you the Best location, best view, best price, nice restaurant, swimming pool, room service, business center, beauty... More

Hotel only $141

8 Hard Rock Hotel Panama Megapolis

5 stars
4.2 / 5 31 reviews

Avenida Balboa Multicentro Map

$20 Drink Credit, $25 Matchplay, FREE WiFi

Rock-and-roll-themed hotel near the Panama CanalThe Hard Rock Hotel Panama Megapolis is a new hotel located right in the center of the city, close to the shops, history and local culture. All sixty-six stories of the 3-star hotel tower block are dedicated to the... More

Hotel only $82

9 The Executive Hotel

3 stars
3.6 / 5 8 reviews

Ave. Aquilino De La Guardia y Cl. 52 Bella Vista Map

FREE Breakfast Buffett, Internet & Local Calls

Situated in the downtown financial district, The Executive Hotel offers well-appointed Panama City boutique hotel accommodations for business and leisure travelers alike. Enjoy a location within walking distance from the city's best dining, shopping, and nightlife. By... More

Hotel only $75

10 Clarion Victoria Hotel and Suites

3 stars
4.0 / 5 31 reviews

Calle D. El Cangrejo Map

Advance Purchase Special - Save 15%

Cozy and convenient hotel in Panama. Get ready to enjoy Panama's newest hotel! Catering to both business and leisure travelers, enjoy spacious accommodations, modern technology and amenities designed with your comfort and convenience in mind. Victoria Hotel & Suites... More