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Santa Cruz Vacations

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Hotel stay must be within date range of Leave and Return.

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Your Santa Cruz vacation

Forget cookie-cutter, pre-packaged vacations. When it comes to Santa Cruz vacations, Orbitz lets you choose the flight and hotel that fits your calendar and price point. Mix and match your Santa Cruz travel plans, and enjoy discounts you won't find when you book separately.

Get expert advice on Santa Cruz travel
Narrow down the best hotels, attractions and activities for your lifestyle and budget. Orbitz offers free 24/7 support so you can plan your Santa Cruz vacations with ease. Call a specialist anytime at 1-800-504-3248.

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View Santa Cruz vacation savings at a glance
See your vacation savings on the Orbitz Matrix Display. View all your flight and hotel options, and see what you can save on Santa Cruz vacations when you book together. It's all you need to know in just one click.

Add activities to Santa Cruz vacations
Skip those long lines, and bundle your flight and hotel vacation packages with activities ahead of time. Book tickets to sightseeing tours, sporting events and more.

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Santa Cruz Vacation Packages

Hotel only $126

1 Esplendor El Calafate

4 stars
4.1 / 5 10 reviews

Pte. Peron 1143 Map


In the Heart of the Argentinean Patagonia stands the Esplendor del Calafate Hotel. Located in the centre of the city, the region's first boutique hotel has a marvelous view of the imposing "Argentino" Lake and the "Calafate" Hill. The city of El... More

2 Don Los Cerros Boutique Hotel & Spa

5 stars
Not yet reviewed

San Martin 260 Map

Save 40%

Don Los Cerros Boutique Hotel & Spa is the hotel emblem of El Chalten. This hotel with personalized 5 star services, is strategically located on a balcony, allowing a unique view of El Chalten valley. The rooms feature large windows, making the landscape a key... More

Hotel only $107

3 Edenia Punta Soberana

4 stars
5.0 / 5 1 reviews

Manzana 642 - Punta Soberana Map

Standing at the top of a hill overlooking the beautiful Lake Argentino, Hotel Edenia offers a real chance to get away from it all. Occupying attractive, low-slung buildings, this hotel has a wonderfully cozy and intimate feel. A great base for exploration of the... More

Hotel only $105

4 Hotel La Aldea

3 stars
4.0 / 5

Av. Guemes N 95 Map

La Aldea Hotel is just for guests that are looking for comfort and good location. The staff is very helpful and you can get easy access to the internet in the reception area which is very comfortable with a lovely welcoming fire when you come in from a cold and wet day... More

Hotel only $74

5 Hosteria Meulen

3 stars
3.0 / 5 2 reviews

Calle 202 Map


In one of the most beautiful landscapes of our Patagonia Argentina, against the Ecological Reserve Nimez Lagoon and to borders of the Argentinean Lake is Meulen, a small Hosteria in El Calafate. We are located to 80 km from the Brown Perito Moreno Glacier. With a... More

Hotel only $144

6 La Cantera Boutique Hotel Calafate

4 stars
4.0 / 5 6 reviews

306th Street, 173 Map


Patagonian Style Boutique Hotel/Lodge with similar services to 5 stars hotel. 20 differently decorated exclusive rooms. Gourmet Restaurant Offers Signature cuisine. The staffs are prepared to provide a highly professional, close and friendly service. Outstanding views to... More

Hotel only $76

7 Hosteria Koi Aiken

3 stars
Not yet reviewed

Calle 102 Nro 3534 Map

Save 20% per night

Koi Aiken is an alternative, a new perspective to approach nature with all the amenities you need to enjoy El Calafate. With good view, the comfort of our facilities, surrounded by hills and a lake few times seen. We create the ideal environment to ensure a memorable stay More

Hotel only $98

8 RH Rochester Calafate

4 stars
3.3 / 5 3 reviews

Av. Libertador 3614 Map

Save 5%

RH Rochester Calafate is located meters away from Bahia Redonda and in front of Argentinian Lake. RH Rochester Calafate outstands thanks to its breathtaking views. It is a few minutes from downtown Calafate and from the Glaciar Perito Moreno area. SERVICES: BREAKFAST... More

Hotel only $287

9 Los Sauces Casa Patagonica

5 stars
4.0 / 5 1 reviews

Los Gauchos 1352/ 70 Map

Save 10% per night

LOS SAUCES Casa Patagonica opened in September 2007 to become the luxury hotel in El Calafate, gateway to Parque Nacional Los Glaciares. LOS SAUCES recreates the hospitable and refined spirit of the Patagonian farms of the beginning of the last century. Its architectural... More

Hotel only $80

10 Rincon del Calafate Hotel

3 stars
3.0 / 5 1 reviews

CALLE 700 N0 273 Map

Save 5% per night

Located in the Patagonian town of El Calafate, bordering on Lake Argentino in the province of Santa Cruz, this 3-star hotel offers cozily furnished double rooms with flat-screen TVs. Rincon Del Calafate is an ideal base all year round for exploring the spectacular local... More