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San Francisco to Mesa Flights

Age of children at time of trip

We will search for applicable airfare discounts. Must have 1 adult for each infant in lap

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Highlighted price = Cheapest round-trip flights

Prices are round trip per person (conditions apply)

Featured Mesa Airport Hotels

Hotel only $32

Econo Lodge Airport

2 stars
3.4 / 5 135 reviews

3037 E. Van Buren Street Map

...Courtesy Airport Shuttle available 24 hours.... Sky Harbor International Airport.... More

Hotel only $77

Holiday Inn Express & Suites PHOENIX AIRPORT

3 stars
4.1 / 5 64 reviews

3401 E. University Drive & I-10 Map

...Welcome to our Contemporary Phoenix Hotel Come experience a memorable stay at one of the finest hotels near the Phoenix airport.... The Holiday Inn Express® Hotel & Suites Phoenix-Airport is... More

Hotel only $86

Hilton Garden Inn Phoenix Airport

3 stars
4.2 / 5 59 reviews

3422 E. Elwood St Map

Complimentary wired and Wi-Fi Internet Access

...Our full service hotel is located just south of Phoenix Sky Harbor International Airport and one block off of Interstate 10 with easy access to all points in the Valley of the Sun.... The Hilton... More

Hotel only $80

BEST WESTERN Airport Inn

3 stars
3.3 / 5 50 reviews

2425 S 24th Street Map

Save 15% on your stay

...Welcome to the BEST WESTERN Airport Inn!.... We are conveniently located 1 mile south of Phoenix Sky Harbor Airport and 1 mile away from the Car Rental Center.... More

Hotel only $41

Days Inn Airport - Phoenix

1 star
2.5 / 5 40 reviews

2900 E. Van Buren Street Map

The Days Inn Phoenix Airport offers a complementary 24 Hr Airport Shuttle to and from Sky Harbor International Airport.... More

Hotel only $80

Hilton Garden Inn Phoenix Airport North

3 stars
4.1 / 5 58 reviews

3838 East Van Buren Street Map

Complimentary wired and Wi-Fi Internet Access

...New airport hotel with first-class style and amenities.... Phoenix Sky Harbor International Airport (1 mi/1.6 km).... More

San Francisco to Mesa Intro 1

Orbitz has your best deals on San Francisco to Mesa flights. From guaranteed low prices to cutting-edge mobile tools, the perfect trip begins on Orbitz.
Get Orbitz On the Go for Flights from San Francisco to Mesa
Use our mobile apps for Android and iPhone to find the best price on flights from San Francisco to Mesa. Check your flight status, gate and baggage claim details, and book exclusive mobile deals on hotels — even on the same day.

Rack Up Miles While Flying for Cheaper

Earn miles or points toward your frequent flyer program on select San Francisco to Mesa flights. When you book your flight on Orbitz, simply add your qualifying frequent flyer number where prompted. You can also store your airline frequent flyer or loyalty program numbers in your Orbitz account profile to automatically add them to your future reservations.

Worry Less With Flight Alerts

Orbitz is the best source for booking flights from San Francisco to Mesa. But we also keep you updated about flight delays, booking changes, or service disruptions with free alerts. Get alerts on San Francisco to Mesa flights sent to your email or via voice or text to your mobile phone. We can also send the alerts to up to 6 other email addresses or phone numbers, which is helpful if you are being picked up at the airport.

Budget Travel Planning Made Easy

It's easy to find discount air tickets for flights from San Francisco to Mesa on Orbitz. Mix and match airlines for your departing and your returning flights to find the lowest fares and the best schedule.