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San Francisco to Knoxville Flights

Flight only Hotel only Flight + Hotel

Flight type

Round-trip One-way
Age of children at time of trip

We will search for applicable airfare discounts. Must have 1 adult for each infant in lap

Selected fares from San Francisco to Knoxville

Departure Arrival Travel dates Round-trip
SFO TYS Tue, Nov 11 - Wed, Nov 19 $390
SFO TYS Tue, Nov 11 - Wed, Nov 19 $541
SFO TYS Tue, Nov 11 - Wed, Nov 19 $541
SFO TYS Sun, Aug 24 - Sun, Aug 31 $544
SFO TYS Sun, Aug 24 - Sun, Aug 31 $572
SFO TYS Fri, Aug 8 - Fri, Aug 22 $1,448

San Francisco and Knoxville airports and terminals

Airports in San Francisco CA, US
map of airports in San Francisco
  • 1

    San Francisco Airport (SFO)

    Distance from City Center: 11.9 miles

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Airports in Knoxville TN, US
map of airports in Knoxville
  • 1

    Knoxville Airport (TYS)

    Distance from City Center: 11.2 miles

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Cheap flights from San Francisco to Knoxville

Sun Mon Tue Wed Thu Fri Sat
1 2 3 4 5 6
7 8 9 10
$390
11 12 13
14 15 16 17
$390
18 19 20
21 22 23 24 25 26 27
28 29 30

Highlighted price = Cheapest round-trip flights

Prices are round trip per person (conditions apply)

Featured Knoxville Airport Hotels

Hotel only $109

Hilton Knoxville Airport

3 stars
4.6 / 5 29 reviews

2001 Alcoa Highway Map

The Hilton Knoxville Airport hotel in Alcoa, Tennessee is connected to McGhee Tyson airport by a covered walkway and is a convenient place to stay whatever your reason for visiting Knoxville.... More

Hotel only $75

La Quinta Inn & Suites Knoxville Airport

3 stars
4.1 / 5 14 reviews

126 Cusick Rd Map

Welcome to the newly remodeled La Quinta Inn & Suites Knoxville Airport hotel, located in the lovely city of Alcoa, rich in Tennessee history.... More

Hotel only $91

Courtyard by Marriott Knoxville Airport Alcoa

3 stars
3.8 / 5 10 reviews

141 Furrow Way Map

Rate includes breakfast

At Courtyard Knoxville Airport Alcoa, we offer comfort, convenience and style.... More

Hotel only $49

Americas Best Value Inn

2 stars
2.6 / 5 14 reviews

2450 Airport Highway Map

Welcome to Americas Best Value Inn Knoxville Airport/Alcoa; conveniently located just off of Highway 129 and minutes away from McGhee Tyson Airport.... More

Hotel only $79

Comfort Suites Airport

2 stars
3.9 / 5 14 reviews

140 Cusick Rd. Map

Located half mile from McGhee Tyson Airport, offering daily shuttle and Stay and Fly packages.... More

Hotel only $67

Country Inn & Suites By Carlson, Knoxville Airport, TN

3 stars
3.8 / 5 71 reviews

162 Cusick Road Map

Save 20% on your stay

...Knoxville airport hotel has free breakfast, Wi-Fi and airport shuttle.... More

September

Cheapest weekend flights in September from San Francisco to Knoxville

Travel dates Departure Arrival Stops: Round-trip
Leave Thu, Sep 25 San Francisco (SFO) Knoxville (TYS) Frontier Airlines $439
Earn $4.39
Return Sun, Sep 28 Knoxville (TYS) San Francisco (SFO) Frontier Airlines

Lowest roundtrip airfare in September from San Francisco to Knoxville

Travel dates Departure Arrival Stops: Round-trip
Leave Wed, Sep 10 San Francisco (SFO) Knoxville (TYS) Frontier Airlines $390
Earn $3.90
Return Wed, Sep 17 Knoxville (TYS) San Francisco (SFO) Frontier Airlines

Best one-week trip in September from San Francisco to Knoxville

Travel dates Departure Arrival Stops: Round-trip
Leave Wed, Sep 10 San Francisco (SFO) Knoxville (TYS) Frontier Airlines $390
Earn $3.90
Return Wed, Sep 17 Knoxville (TYS) San Francisco (SFO) Frontier Airlines
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October

Cheapest weekend flights in October from San Francisco to Knoxville

Travel dates Departure Arrival Stops: Round-trip
Leave Thu, Oct 9 San Francisco (SFO) Knoxville (TYS) Frontier Airlines $475
Earn $4.75
Return Sun, Oct 12 Knoxville (TYS) San Francisco (SFO) Frontier Airlines

Lowest roundtrip airfare in October from San Francisco to Knoxville

Travel dates Departure Arrival Stops: Round-trip
Leave Wed, Oct 22 San Francisco (SFO) Knoxville (TYS) Frontier Airlines $390
Earn $3.90
Return Wed, Oct 29 Knoxville (TYS) San Francisco (SFO) Frontier Airlines

Best one-week trip in October from San Francisco to Knoxville

Travel dates Departure Arrival Stops: Round-trip
Leave Wed, Oct 22 San Francisco (SFO) Knoxville (TYS) Frontier Airlines $390
Earn $3.90
Return Wed, Oct 29 Knoxville (TYS) San Francisco (SFO) Frontier Airlines
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November

Lowest roundtrip airfare in November from San Francisco to Knoxville

Travel dates Departure Arrival Stops: Round-trip
Leave Tue, Nov 11 San Francisco (SFO) Knoxville (TYS) Frontier Airlines $390
Earn $3.90
Return Wed, Nov 19 Knoxville (TYS) San Francisco (SFO) Frontier Airlines
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Flights to Knoxville

San Francisco International Airport Information

The San Francisco International Airport (Highway 101 near the junction of Highway 380) is the primary commercial passenger airport serving San Francisco and the surrounding areas. The airport hosts most international and domestic airlines offering cheap flights from San Francisco. You can also use Orbitz.com to book an alternate flight out of Oakland International Airport (1 Oakland Drive, Oakland) or San Jose International Airport (2065 Airport Boulevard, San Jose).

Parking at San Francisco International Airport

San Francisco International's parking garages are a 10-minute walk or less from the gates, and there is free shuttle service from the long-term lots. Parking costs anywhere from $18 to $38 per day, depending on the option you choose. If you've used Orbitz.com to book your discount flights, you may have saved enough to justify spending the extra money to use the airport's valet parking service.

Ground Transportation Information

A taxi, limousine or shared-ride van to the airport will cost anywhere from $17 to $40. Factor in plenty of extra travel time for the 13-mile ride, as rush-hour traffic can be brutal. You can also use the public BART system or the SamTrans public bus service, both of which will cost you less than $10. Don't forget to use Orbitz.com before you leave to book a rental car in your destination city.

Restaurant Options at the Airport

The San Francisco airport has roughly 50 eateries where you can grab a coffee or have a light meal. Most of the restaurants and cafes are located within the terminals past the security checkpoint, but there are a few restaurants before you reach the security gates. Have a great flight to your final destination, and don't forget to use Orbitz.com the next time you're looking for cheap flights from San Francisco.

Knoxville Airport Information

Visitors coming to the Knoxville area usually fly into the McGhee Tyson Airport, just 14 miles south of the city. When you use Orbitz.com to book cheap flights to Knoxville, you will be able to choose from all of the major airlines that serve the airport, including Allegiant, American Airlines, Delta, Frontier, United and US Airways.

Ground Transportation in Knoxville

Knoxville doesn't offer much in the way of public transportation, but you will have your choice of shuttle vans, taxis and private car and limousine services to take you to your final destination. Orbitz.com can help you choose a rental car to get around while you are in the Knoxville area. You can also use Orbitz to book a hotel that offers free shuttle service to and from the airport.

Knoxville Area Weather Information

Knoxville winters can be chilly, with temperatures in the 20s, 30s and 40s, so make sure to pack a winter jacket or fleece to keep you warm. Summers are warm, with temperatures ranging from the high 60s to the high 80s. July usually sees the highest average rainfall, so be sure to pack a lightweight rain slicker or umbrella to keep you dry.

What to Do in Knoxville

Knoxville combines small-town Southern charm with the fun and activities you would expect to find in a big city. You can spend your time playing golf, visiting museums or touring some of the area's historical landmarks, but be sure not to miss the area's famous festivals and celebrations. Some of the city's most popular events include the Boomsday, Rossini and Dogwood Arts festivals and the Knoxville Brewers Jam. Enjoy your time in the city, and remember to use Orbitz.com the next time you want to book cheap flights to Knoxville.