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San Diego to Columbia Flights

Flight only Hotel only Flight + Hotel

Flight type

Round-trip One-way
Age of children at time of trip

We will search for applicable airfare discounts. Must have 1 adult for each infant in lap

San Diego and Columbia airports and terminals

Airports in San Diego CA, US
map of airports in San Diego
  • 1

    San Diego Airport (SAN)

    Distance from City Center: 2 miles

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Airports in Columbia MO, US
map of airports in Columbia
  • 1

    Columbia Regional (COU)

    Distance from City Center: 11 miles

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Cheap flights from San Diego to Columbia

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Highlighted price = Cheapest round-trip flights

Prices are round trip per person (conditions apply)

Featured Columbia Airport Hotels

Hotel only $86

Holiday Inn Express & Suites COLUMBIA UNIV AREA - HWY 63

3 stars
4.6 / 5 8 reviews

1402 Cinnamon Hill Lane Map

...Area-Hwy 63 offers easy access to many area attractions including the Downtown District, Faurot Field Football Stadium, Hearnes Arena, Mizzou Arena & the Columbia Regional Airport.... More

Hotel only $52

Baymont Inn & Suites Columbia

2 stars
3.3 / 5 7 reviews

801 Keene Street Map

Stay 3, Save 20%

Enjoy the hometown hospitality at this Baymont Inn and Suites Columbia, just off Interstate 70 and Highway 63, convenient to Columbia Regional Airport, Columbia Regional Hospital, the University of... More

Hotel only $65

Wingate by Wyndham Columbia

2 stars
3.5 / 5 39 reviews

3101 Wingate Court Map

Stay 3, Save 20%

Conveniently located off Interstate 70, this Wingate by Wyndham Columbia is near Columbia Regional Airport, downtown Columbia, University of Missouri, Boone County Fairgrounds, shopping and many... More

Hotel only $54

Suburban Extended Stay Hotel Columbia - Hwy 63 & I-70

2 stars
3.3 / 5 6 reviews

3100 Wingate Court Map

The Suburban Extended Stay Hotel in Columbia, Missouri is near University of Missouri and its sports fields, Columbia Regional Hospital and downtown Columbia.... More

Hotel only $51

Budget Host Columbia

2 stars
2.2 / 5 43 reviews

900 Vandiver Dr Map

Save 10% on your stay

Our petfriendly Columbia MO hotel is close to Interstate 70 and within easy reach of great restaurants and the area attractions we are known for. Our 24hour front desk staff is always ready to... More

Motel 6 Columbia - West

1 star
2.6 / 5 41 reviews

1800 I-70 Dr Southwest Map

This Motel 6 offers a wide variety of amenities including: 24-hour front desk service, facilities for persons with disabilities and complimentary coffee. For a nominal charge fax services are... More

San Diego to Columbia Intro 14

Orbitz combines guaranteed low prices with cutting-edge mobile tools for travel from San Diego to Columbia to give you a travel experience that is second to none.

Bargain Travel at Your Fingertips

Orbitz provides the cheapest fares from San Diego to Columbia. When reserving your flight you can mix and match a range of low cost airlines for you departing and returning domestic or international flights. This way you can travel on a budget while selecting the flights that suit your schedule.

Modern Tools for Fast-Paced Travel

Orbitz makes use of the latest technology to ensure that you are always kept up-to-date on the status of your San Diego to Columbia flights. Through easy-to-use mobile Android and iPhone apps you can book low cost flights from San Diego to Columbia and choose a range of cheap hotels to stay in.

Enjoy Stress-Free Travel with Flight Alerts

Once you have booked your flights from San Diego to Columbia on Orbitz you will always be kept informed of any changes to your flight. When you opt into Orbitz’s free email and SMS alerts on your San Diego to Columbia flights you can ask Orbitz to send the flight details to up to 6 other contacts, so keeping your family and business team informed is a cinch.

Frequent Flyer Program

For loyal Orbitz customers who fly from San Diego to Columbia the chance to join our frequent flyer program is an added bonus. Simply log-on to your online account and input your frequent flyer number for future flights.