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Orlando to Florence Flights

Flight only Hotel only Flight + Hotel

Flight type

Round-trip One-way
Age of children at time of trip

We will search for applicable airfare discounts. Must have 1 adult for each infant in lap

Orlando and Florence airports and terminals

Airports in Orlando FL, US
map of airports in Orlando
  • 1

    Orlando Airport (MCO)

    Distance from City Center: 14.5 miles

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Airports in Florence SC, US
map of airports in Florence
  • 1

    Florence Airport (FLO)

    Distance from City Center: 3.2 miles

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Cheap flights from Orlando to Florence

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Highlighted price = Cheapest round-trip flights

Prices are round trip per person (conditions apply)

Featured Florence Airport Hotels

Country Hearth Inn Florence

3 stars
2.1 / 5 20 reviews

831 South Irby Street Map

...Located next to downtown Florence - 5 minutes from the Bus Depot, 10 minutes from Amtrak Train Station, 10 minutes from Florence Regional Airport.... More

Hotel only $62

Ramada Florence Center

2 stars
2.8 / 5 44 reviews

1819 West Lucas Street Map

Stay 3, Save 20%

...This Florence hotel is just minutes to downtown Florence and the Darlington International Speedway, also located only 5 Miles from the Florence Regional Airport and Amtrak Station.... More

Hotel only $55

Baymont Inn & Suites Florence

2 stars
3.5 / 5 44 reviews

1826 West Lucas Street Map

Stay 3, Save 20%

Enjoy the southern hospitality at this Baymont Inn and Suites Florence, just off Interstate 95 and minutes from the Florence Regional Airport, many corporate offices, the Florence Civic Center,... More

Hotel only $46

Suburban Extended Stay Hotel

2 stars
3.2 / 5 90 reviews

1914 West Lucas Street I-95 & US 52 Map

When you stay at a Suburban Extended Stay Hotel, you can rest assured that you're getting a good deal. You will have your own in-room kitchen, on site laundry, FREE cable TV, and Internet/data... More

Hotel only $37

Hotel Carolina

1 star
1.7 / 5 21 reviews

1811 West Lucas Street Map

The Hotel Carolina of Florence is less than 9 miles from Darlington Raceway and 5 miles from the Florence Airport.... More

Hotel only $67

Red Roof Inn Florence Civic Center

2 stars
3.2 / 5 51 reviews

2690 David McLeod Blvd Map

Magnolia Mall, with 70 great stores, is right across the street. We are adjacent to the Florence City-County Civic Center; Darlington International Raceway is just 12 miles and North Carolina... More

Orlando to Florence Intro 5

Orbitz is the best place to find guaranteed low prices on Orlando to Florence flights. Because of our cutting-edge mobile tools and low fares on domestic and international flights, Orbitz is the best starting point for travelers.

Find Cheap Orlando to Florence Flights

Orbitz offers free mobile apps for iPhone and Android devices—a great way to find fantastic deals on flights from Orlando to Florence. Not only that, but you can check the status of your flight or even book low cost hotel rooms with the apps or on m.orbitz.com.

Get Miles and Points for Your Flight

Simply enter your frequent flyer information while booking to get miles or points for qualifying Orlando to Florence flights. This information can all be saved in your Orbitz account, which means it will not have to be entered each time you take advantage of a great air fare deal.

Flight Alerts Take Away the Stress

Orbitz does not want travelers to worry on their flights from Orlando to Florence. We keep you updated on any flight changes for Orlando to Florence flights with alerts sent directly to your email or a mobile device. These alerts can also be sent to friends and family.

Discount Travel Planning Made Simple

You will have no problems finding budget flights from Orlando to Florence on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.