Flights from Orlando to Florence

Selected fares from Orlando to Florence

Departure Arrival Travel dates Round-trip
ORL FLO Tue, Dec 15 - Thu, Dec 31 $260
ORL FLO Thu, Dec 17 - Sun, Jan 3 $415
Sun Mon Tue Wed Thu Fri Sat
1 2 3 4
5 6 7
$287
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26 27 28 29 30 31

Highlighted price = Cheapest round-trip flights

Prices are round trip per person (conditions apply)

Orlando and Florence airports and terminals

Airports in Orlando FL, US

map of airports in Orlando
  • 1

    Orlando Airport (MCO)

    Distance from City Center: 14.5 miles

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Airports in Florence SC, US

map of airports in Florence
  • 1

    Florence Airport (FLO)

    Distance from City Center: 3.2 miles

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Featured Florence Airport Hotels

From $49

Country Hearth Inns and Suites Florence

2 stars
2.1 / 5 12 reviews

831 S Irby Street Map

Country Hearth Inn Florence offers the most value for your money when staying for business- pleasure- or just passing through. We offer clean spacious rooms- free continental breakfast- coffee/tea... More

From $62

Ramada Florence Center

2 stars
2.5 / 5 34 reviews

1819 West Lucas Street Map

Stay 2, Save 15%

Refresh at this Ramada Florence Center hotel conveniently located off Interstate 95 near Florence Regional Airport, NASCAR races at Darlington Raceway, NASCAR Stock Car Museum, Florence Civic... More

From $55

Baymont Inn & Suites Florence

2 stars
3.5 / 5 33 reviews

1826 West Lucas Street Map

Stay 3, Save 20%

Enjoy the southern hospitality at this Baymont Inn and Suites Florence, just off Interstate 95 and minutes from the Florence Regional Airport, many corporate offices, the Florence Civic Center,... More

From $48

Suburban Extended Stay Hotel

2 stars
3.0 / 5 67 reviews

1914 West Lucas Street I-95 & US 52 Map

When you stay at a Suburban Extended Stay Hotel, you can rest assured that you're getting a good deal. You will have your own in-room kitchen, on site laundry, FREE cable TV, and Internet/data... More

From $84

La Quinta Inn & Suites Florence

3 stars
3.4 / 5 22 reviews

2123 West Lucas Street Map

...Conveniently located right off I-95 just minutes from the Florence Regional Airport, and Darlington Raceway/Museum.... More

July

Lowest roundtrip airfare in July from Orlando to Florence

Travel dates Departure Arrival Stops: Round-trip
Leave Tue, Jul 7 Orlando (MCO) Florence (FLO) US Airways $287
Earn $2.87
Return Wed, Jul 8 Florence (FLO) Orlando (MCO) US Airways
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Orlando to Florence Intro 17

If you are looking online for bargain Orlando to Florence flights, Orbitz is your ideal destination. We understand that vacations can be expensive and offer guaranteed low prices on our domestic and international tickets.

Orbitz Uses Cutting-Edge Mobile Tools

Orbitz may offer low cost Orlando to Florence flights but this does not mean that we skimp on giving you the latest mobile apps. You don’t have to worry about checking your flight status as we send the info for your flights from Orlando to Florence directly to your smartphone.

Fly Cheap and Earn Miles on Your Orlando to Florence Flights

Frequent flyer miles and points are great—and even better when you earn them on cheap flights from Orlando to Florence. With Orbitz, you can earn miles for your frequent flyer program on qualified flights. Enter your frequent flyer number when you book with us to get rewarded for your flight.

Orbitz Takes the Hassle Out Of Flying

We know that flying can be stressful, particularly if you are traveling with young children. That’s why we make sure you are aware of any changes or delays to your flights from Orlando to Florence via your phone or email address. We can even inform family members too.

Orbitz Flights Fit Around Your Lifestyle

Orbitz understands that you don’t necessarily want to fly at 5:00 a.m—and that sometimes you do. This is why we allow you to find the best Orlando to Florence flights at the times you want with ease.