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Detroit to Cape Girardeau Flights

Flight only Hotel only Flight + Hotel

Flight type

Round-trip One-way
Age of children at time of trip

We will search for applicable airfare discounts. Must have 1 adult for each infant in lap

Detroit and Cape Girardeau airports and terminals

Airports in Detroit MI, US
map of airports in Detroit
  • 1

    Detroit Wayne County Airport (DTW)

    Distance from City Center: 17.5 miles

  • 2

    Willow Run (YIP)

    Distance from City Center: 26 miles

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Airports in Cape Girardeau MO, US
map of airports in Cape Girardeau
  • 1

    Williamson County (MWA)

    Distance from City Center: 42.6 miles

  • 2

    Cape Girardeau Airport (CGI)

    Distance from City Center: 5.3 miles

  • 3

    Barkley Regional (PAH)

    Distance from City Center: 46.1 miles

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Cheap flights from Detroit to Cape Girardeau

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Highlighted price = Cheapest round-trip flights

Prices are round trip per person (conditions apply)

Featured Cape Girardeau Airport Hotels

Hotel only $92

Candlewood Suites CAPE GIRARDEAU

2 stars
4.5 / 5 11 reviews

485 SOUTH MOUNT AUBURN ROAD Map

Experience Historic Cape Girardeau from Hotel's Suites A historic college town in southeastern Missouri, Cape Girardeau is bordered on the east by the mighty Mississippi River.... More

Hotel only $112

Holiday Inn Express & Suites CAPE GIRARDEAU I-55

3 stars
4.6 / 5 30 reviews

3253 WILLIAM ST. Map

Welcome to Our Cape Girardeau Hotel.... More

Hotel only $81

Auburn Place Hotel and Suites

2 stars
4.5 / 5 17 reviews

3265 William St. Map

Free breakfast with over 25 items, indoor heated pool, large whirlpool, free high speed wireless internet in every room, located right off of I-55, microwaves and refrigerators in every room, and... More

Hotel only $119

Hampton Inn Cape Girardeau

3 stars
3.0 / 5 1 reviews

103 Cape West Parkway Map

escape to the cape...welcome to the Hampton Inn Cape Girardeau.... More

Drury Lodge Cape Girardeau

3 stars
3.9 / 5 50 reviews

104 South Vantage Drive Map

The Extras Aren't Extra at Drury Hotels. Your great rate includes FREE hot food and cold beverages at our 5:30 Kickback. FREE hot breakfast, FREE wireless Internet access and FREE long distance.... More

Hotel only $73

Pear Tree Inn Cape Girardeau

2 stars
3.7 / 5 51 reviews

3248 William Street Map

The Extras Aren't Extra! Your great rate includes FREE evening snacks and beverages. FREE breakfast, FREE wireless Internet access and FREE long distance. Don't miss our great breakfast buffet. ... More

Detroit to Cape Girardeau Intro 22

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We help take some of the anxiety out of your Detroit to Cape Girardeau flights with free flight alerts. We will let you know of flight changes and delays to your flights from Detroit to Cape Girardeau by email, voicemail, or text messages to your mobile phone. Alerts can also be sent to up to six other contacts to keep family and business teams informed.

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