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Des Moines to Los Angeles Flights

Orbitz gives you great deals on your flights from Des Moines to Los Angeles. If you also need a discount car rental or a cheap hotel room after you arrived at your destination, Orbitz has you covered.

We Offer Great Travel Deals and Discounts

When you book flights from Des Moines to Los Angeles with Orbitz for, you can be assured that you are getting the lowest price possible. Orbitz works constantly with our airline partners to ensure guaranteed low prices on Des Moines to Los Angeles flights for your trip—whether you are traveling for business or for fun with your family.

Enjoy Savings on Last-Minute Flights

If you are looking for a discount price on last-minute flights from Des Moines to Los Angeles, chances are that Orbitz can offer you a deal that will save you lots of money. Whether you just want to get away for the weekend or go on a vacation lasting weeks, Orbitz can help you find the best deals on Des Moines to Los Angeles flights that fit your budget and your itinerary for the perfect trip.

Full-Service Mobile Apps

Need more mobility when it comes to travel planning? Orbitz has easy-to-use mobile apps for iPhone, iPad, and Android, to help the traveler on the go. Not only can use the apps to find huge savings on Des Moines to Los Angeles flights wherever you are, but you can also check out and book discount hotel rooms too. The apps will also keep you up-to-date when it’s time to fly. Get easy access to your itinerary for flights from Des Moines to Los Angeles and review gate and baggage claim details too.

Cheap flights from Des Moines to Los Angeles

Prices are for round-trip flights per adult (taxes and fees included)

Cheapest fares highlighted below

Previous May
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Sun Mon Tue Wed Thu Fri Sat
27 28 29 30 31 1 $482 2 $551
3 $469 4 $454 5 Search this date 6 Search this date 7 $393 8 Search this date 9 Search this date
10 Search this date 11 Search this date 12 $1,350 13 $386 14 $371 15 $406 16 Search this date
17 Search this date 18 Search this date 19 Search this date 20 Search this date 21 $430 22 $371 23 Search this date
24 $461 25 $445 26 $430 27 Search this date 28 $465 29 $351 30 Search this date

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 48 hours. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.