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Cleveland to Florence Flights

Flight only Hotel only Flight + Hotel

Flight type

Round-trip One-way
Age of children at time of trip

We will search for applicable airfare discounts. Must have 1 adult for each infant in lap

Cleveland and Florence airports and terminals

Airports in Cleveland OH, US
map of airports in Cleveland
  • 1

    Hopkins International (CLE)

    Distance from City Center: 9.5 miles

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Airports in Florence SC, US
map of airports in Florence
  • 1

    Florence Airport (FLO)

    Distance from City Center: 3.2 miles

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Cheap flights from Cleveland to Florence

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Highlighted price = Cheapest round-trip flights

Prices are round trip per person (conditions apply)

Featured Florence Airport Hotels

Hotel only $49

Country Hearth Inns and Suites Florence

2 stars
2.1 / 5 12 reviews

831 S Irby Street Map

Country Hearth Inn Florence offers the most value for your money when staying for business- pleasure- or just passing through. We offer clean spacious rooms- free continental breakfast- coffee/tea... More

Hotel only $62

Ramada Florence Center

2 stars
2.5 / 5 34 reviews

1819 West Lucas Street Map

Stay 2, Save 15%

Refresh at this Ramada Florence Center hotel conveniently located off Interstate 95 near Florence Regional Airport, NASCAR races at Darlington Raceway, NASCAR Stock Car Museum, Florence Civic... More

Hotel only $55

Baymont Inn & Suites Florence

2 stars
3.5 / 5 33 reviews

1826 West Lucas Street Map

Stay 3, Save 20%

Enjoy the southern hospitality at this Baymont Inn and Suites Florence, just off Interstate 95 and minutes from the Florence Regional Airport, many corporate offices, the Florence Civic Center,... More

Hotel only $48

Suburban Extended Stay Hotel

2 stars
3.0 / 5 67 reviews

1914 West Lucas Street I-95 & US 52 Map

When you stay at a Suburban Extended Stay Hotel, you can rest assured that you're getting a good deal. You will have your own in-room kitchen, on site laundry, FREE cable TV, and Internet/data... More

Hotel only $84

La Quinta Inn & Suites Florence

3 stars
3.4 / 5 22 reviews

2123 West Lucas Street Map

...Conveniently located right off I-95 just minutes from the Florence Regional Airport, and Darlington Raceway/Museum.... More

Hotel only $59

Red Roof Inn Florence Civic Center

2 stars
3.4 / 5 41 reviews

2690 David McLeod Blvd Map

Magnolia Mall, with 70 great stores, is right across the street. We are adjacent to the Florence City-County Civic Center; Darlington International Raceway is just 12 miles and North Carolina... More

Cleveland to Florence Intro 17

If you are looking online for bargain Cleveland to Florence flights, Orbitz is your ideal destination. We understand that vacations can be expensive and offer guaranteed low prices on our domestic and international tickets.

Orbitz Uses Cutting-Edge Mobile Tools

Orbitz may offer low cost Cleveland to Florence flights but this does not mean that we skimp on giving you the latest mobile apps. You don’t have to worry about checking your flight status as we send the info for your flights from Cleveland to Florence directly to your smartphone.

Fly Cheap and Earn Miles on Your Cleveland to Florence Flights

Frequent flyer miles and points are great—and even better when you earn them on cheap flights from Cleveland to Florence. With Orbitz, you can earn miles for your frequent flyer program on qualified flights. Enter your frequent flyer number when you book with us to get rewarded for your flight.

Orbitz Takes the Hassle Out Of Flying

We know that flying can be stressful, particularly if you are traveling with young children. That’s why we make sure you are aware of any changes or delays to your flights from Cleveland to Florence via your phone or email address. We can even inform family members too.

Orbitz Flights Fit Around Your Lifestyle

Orbitz understands that you don’t necessarily want to fly at 5:00 a.m—and that sometimes you do. This is why we allow you to find the best Cleveland to Florence flights at the times you want with ease.