Orbitz is pleased to offer airline tickets on US Airways, which operates a non-stop flight Saturdays from San Diego (SAN) to Puerto Vallarta, Mexico (PVR), regularly scheduled to depart at 2:06pm and arrive at 6:43pm. Usually a Canadair Regional Jet 900 is flown for this route. The average travel time from San Diego, CA to Puerto Vallarta, Mexico is 2 hours and 37 minutes.