As part of booking roundtrip flights which depart from US airports, Orbitz is pleased to offer airline tickets on United Airlines, which operates a daily non-stop flight from Mexico City, Mexico (MEX) to Charlotte (CLT) regularly scheduled to depart at 1:40pm and arrive at 6:09pm. Usually a Boeing 757 is flown for this route. The average travel time from Mexico City, Mexico to Charlotte, NC is 3 hours and 29 minutes.